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Pharmacy, clinic and prescribers based in Greater Manchester.
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Variety of delivery options including next day & free delivery.
Pharmacy, clinic and prescribers based in Greater Manchester.
Start your treatment with a quick and free online consultation.
Fill in a quick online consultation for our licensed pharmacists to review.
Our pharmacists will review your treatment to ensure it’s suitable.
Your treatment will be delivered to your door quickly & discreetly.
Aklief Cream is a prescription-only topical retinoid used to treat acne on the face and trunk in adults and adolescents aged 12 years and older. It contains trifarotene 50 micrograms per gram, a fourth-generation retinoid that helps reduce blocked pores, blackheads, whiteheads, and inflammatory pimples.
Aklief works by regulating skin cell turnover and preventing pores from becoming clogged, reducing the number of acne lesions and improving skin texture. It is applied once daily to affected areas and is suitable for mild to moderate acne with comedones and inflammatory spots.
| Medication Name | Aklief Cream |
| Active Ingredient | Trifarotene 50 micrograms per gram |
| Medication Form | Topical cream |
| Used to Treat | Acne vulgaris affecting the face and/or trunk |
| Available Size | 75g pump |
| Who Can Use It | Adults and adolescents aged 12 years and above |
| Prescription Required? | Yes |
| How to Use | Apply a thin layer once daily in the evening to clean, dry skin on affected areas of the face or trunk as directed by your doctor. |
| Patient Information Leaflet | Aklief Cream – Patient Information Leaflet |
Aklief Cream is used for the treatment of acne vulgaris by reducing inflammation and preventing blocked pores. It targets both comedonal and inflammatory acne, helping to improve overall skin clarity and texture on the face, chest, shoulders, and back.
Aklief is suitable for adults and adolescents aged 12 years and over who have acne on the face or trunk.
Do not use Aklief if you:
Consult your doctor if you are breastfeeding. Do not apply the cream to the chest area during breastfeeding.
You may use a moisturiser before or after applying Aklief to reduce dryness and irritation. Allow skin to dry between applications.
Like all medicines, Aklief can cause side effects, although not everyone will experience them. Most side effects are mild and occur at the site of application.
If you experience severe redness, burning, or irritation, stop using Aklief and contact your doctor.
Active ingredient: Trifarotene 50 micrograms per gram.
Other ingredients: Allantoin, cyclomethicone, ethanol, phenoxyethanol, propylene glycol (E1520), medium-chain triglycerides, purified water, and other emulsifiers.
Aklief Cream is available through our acne treatment clinic following an online consultation with one of our qualified prescribers. Once approved, your medication will be dispensed and delivered discreetly to your door.
EXCELLENT Based on 121 reviews Posted on Shabbeer Ahmad13/10/2024 Nice local pharmacyPosted on Hema Mehta06/09/2024 Very friendly and helpful. Moved my order to urgent as was needed in a certsin timeframe. So grateful for their help and service.Posted on Eitha Caines05/09/2024 Very helpful and politePosted on Uju Udedibia30/08/2024 Great experience and an amazing, receptive and lovely staff. I recommend this pharmacy.Posted on Lindsey Whitaker22/08/2024 I had my blood taken today by the lovely lady at the pharmacy. It was a really great service and so reasonably priced. I will definitely be using their phlebotomy services again.Posted on Joanne Royle22/08/2024 Wonderful service I went for diabetes test after failing to getting sorted with my own doctors. Lady that did my test was fantastic. The staff are friendly and very welcoming. I would recommend them 100%. I will definitely use them again in the futurePosted on Ifeanyi Ohanyere16/08/2024 I visited the pharmacy to do a genotype test. The staff were so kind and supportive as I was coming from out of town. Turn around was quick. I highly recommend.
Aklief Cream is used to treat acne vulgaris on the face and trunk by unblocking pores, reducing inflammation, and preventing new spots from forming.
Apply once daily in the evening to clean, dry skin on affected areas using a thin layer. Avoid contact with eyes and lips.
Yes, you can apply a moisturiser before or after Aklief to reduce dryness or irritation, allowing time between applications for the skin to dry.
No, Aklief must not be used during pregnancy or if planning to conceive. Stop use immediately if you become pregnant.
You can buy Aklief Cream 75g online from Click2Pharmacy after a quick consultation with one of our prescribers, with discreet home delivery.
Page content authored by Amjad Khan, last reviewed by Mr Muhammad on 3rd November 2025.




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