Vagifem

About Vagifem

What is Vagifem?

Vagifem is a vaginal tablet that contains the hormone estradiol, a form of oestrogen. It is specifically designed to treat symptoms of vaginal atrophy, such as dryness, itching, and discomfort, which often occur during menopause. Vagifem delivers a small amount of oestrogen directly to the vaginal tissues, helping to restore moisture and elasticity.

What is Vagifem used for?

Vagifem is primarily used to treat vaginal dryness, a common symptom of menopause. This condition can cause discomfort, itching, and pain during intercourse. Vagifem helps alleviate these symptoms by replenishing the oestrogen levels in the vaginal tissues. In addition to treating vaginal dryness, Vagifem may also be used to address other menopausal symptoms affecting the vaginal area, such as irritation and inflammation.

How does Vagifem work?

Vagifem works by releasing estradiol, a form of oestrogen, directly into the vaginal tissues. During menopause, the body’s natural oestrogen levels decrease, leading to thinning and drying of the vaginal walls. By delivering estradiol locally, Vagifem helps to replenish the oestrogen levels in the vaginal tissues. This process restores the natural moisture and thickness of the vaginal walls, reducing dryness, itching, and discomfort. The localised delivery ensures that the hormone acts directly where it is needed, with minimal absorption into the bloodstream.

Who is Vagifem suitable for?

Vagifem is suitable for women experiencing symptoms of vaginal atrophy due to menopause. It is particularly beneficial for those who suffer from vaginal dryness, itching, and discomfort. However, Vagifem may not be suitable for everyone. Women who have a history of breast cancer, unexplained vaginal bleeding, or blood clots should avoid using Vagifem. Additionally, those with liver disease, porphyria, or a known allergy to any of the ingredients should not use this medication. Always consult your doctor or pharmacist before starting Vagifem to ensure it is appropriate for your condition.

How to use Vagifem

• Wash your hands thoroughly before handling the tablet.
• Remove the applicator from its packaging.
• Insert the applicator into the vagina as far as it comfortably goes.
• Press the plunger to release the tablet into the vagina.
• Remove the applicator and dispose of it properly.
• Wash your hands again after use.

Use Vagifem once daily for the first two weeks. After this initial period, reduce the frequency to twice a week, with at least three days between doses.

Continue using Vagifem for as long as your doctor or pharmacist recommends. The duration of treatment may vary depending on your symptoms and response to the medication.

Vagifem Side Effects

Like all medications, Vagifem can cause side effects. Below are some common, uncommon, and serious side effects you may experience.

Common Side Effects

• Headache
• Abdominal pain
• Vaginal discharge
• Vaginal bleeding or spotting

Uncommon Side Effects

• Nausea
• Back pain
• Weight gain
• Breast pain

Serious Side Effects

• Severe allergic reactions (rash, itching, swelling)
• Blood clots
• Stroke
• Heart attack

For a full list of side effects, please refer to the patient information leaflet.

Vagifem Ingredients

Active Ingredients: The active ingredient in Vagifem is estradiol.

Other Ingredients: Vagifem also contains hypromellose, lactose monohydrate, maize starch, and magnesium stearate.

Important Information

• Do not use Vagifem if you are allergic to estradiol or any other ingredients in the tablet.
• Do not use Vagifem if you have a history of breast cancer or any other oestrogen-dependent cancer.
• Do not use Vagifem if you have unexplained vaginal bleeding.
• Do not use Vagifem if you have a history of blood clots or thrombophlebitis.
• Do not use Vagifem if you have liver disease or porphyria.
• Inform your doctor or pharmacist if you have a history of endometriosis or fibroids.
• Inform your doctor or pharmacist if you have high blood pressure, diabetes, or migraines.
• Inform your doctor or pharmacist if you are pregnant or breastfeeding.