Spedra Tablets 50mg, 100mg and 200mg (Avanafil)

From £27.50

  • Spedra Tablets (Avanafil) 50mg,100mg,200mg
  • Available in a Pack of 4 Tablets
  • Multi Buy Options
  • Improves Erectile Function and Increases Blood Flow
  • Enhances Sexual Performance
  • Fast acting – works within 1 hour and lasts up to 4 hours
  • Buy online from a UK-licensed pharmacy following a free consultation

Spedra 50mg tablets

50mg | 1 x 4 tablets | £27.50

50mg | 2 x 4 tablets | £49.00

50mg | 3 x 4 tablets | £69.00

50mg | 4 x 4 tablets | £88.00

50mg | 5 x 4 tablets | £105.00

Spedra 100mg tablets

100mg | 1 x 4 tablets | £32.50

100mg | 2 x 4 tablets | £60.00

100mg | 3 x 4 tablets | £84.00

100mg | 4 x 4 tablets | £104.00

100mg | 5 x 4 tablets | £130.00

Spedra 200mg tablets

200mg | 1 x 4 tablets | £42.00

200mg | 2 x 4 tablets | £74.00

200mg | 3 x 4 tablets | £108.99

200mg | 4 x 4 tablets | £141.00

200mg | 5 x 4 tablets | £173.99

Fast & Free Delivery Options

Variety of delivery options including next day & free delivery.

100% UK-based Pharmacy

Pharmacy, clinic and prescribers based in Greater Manchester.

Free Online Consultations

Start your treatment with a quick and free online consultation.

Complete a free online assessment to buy your preferred treatment.
Continue to assessment
Fast & Free Delivery Options

Variety of delivery options including next day & free delivery.

100% UK-based Pharmacy

Pharmacy, clinic and prescribers based in Greater Manchester.

Free Online Consultations

Start your treatment with a quick and free online consultation.

Buy Spedra Online

Step 1: Online Consultation

Fill in a quick online consultation for our licensed pharmacists to review.

Step 2: Choose a Treatment

Our pharmacists will review your treatment to ensure it’s suitable.

Step 3: Quick & Discreet Delivery

Your treatment will be delivered to your door quickly & discretely.

About Spedra Tablets

Spedra, or branded Avanafil, is an erectile dysfunction medication for men over the age of 18. Designed to address issues related to maintaining an erection, Spedra offers a solution for those seeking to improve their sexual performance.

Medication Name Spedra
Active Ingredient Avanafil
Dosage 50mg, 100mg, 200mg
Medication Form Tablets
Used to Treat Erectile Dysfunction
Available as Branded Avanafil
Common Side Effects Headache, skin flushing, nasal congestion
Who is the medication suitable for Men over the age of 18
Does it require a prescription? Yes
How should it be used? Take one 15-30 minutes before sex
Patient Information Leaflet Spedra Patient Information Leaflet 

How does Spedra work?

Spedra works by helping to relax the blood vessels in your penis, allowing blood to flow into your penis when you get sexually excited. Spedra only helps you to get an erection if you are sexually stimulated. It is intended for use in adult men with erectile dysfunction, which is the inability to achieve or maintain a hard, erect penis suitable for sexual activity.

What is Spedra used for?

Spedra is a treatment for men facing challenges with erectile dysfunction, helping to support an erection in the context of sexual stimulation.

How to take Spedra Tablets

Take one Spedra tablet about 30 minutes before sexual activity, and don’t take more than once a day. Follow your GP or pharmacist’s instructions on dosage, usually starting with a middle dose, adjusting based on effectiveness and tolerance.

Swallow the tablet whole with water and take it with or without food, but heavy meals might slow its effect.

Spedra Dosage

Spedra tablets come in doses of 50 mg, 100 mg, and 200 mg tablets. The usual dose is 100 mg, but your GP or pharmacist might adjust this based on effectiveness and side effects.

For those on certain medications, like moderate CYP3A4 inhibitors, the dose might be adjusted, and a 100 mg tablet might be recommended with at least 2 days between doses. Depending on how you respond, you might be prescribed a lower dose (Spedra 50 mg) or a higher dose (Spedra 200 mg).

Spedra Ingredients

Active Ingredient: Avanafil

Inactive Ingredient: Mannitol, Fumaric acid, Hydroxypropylcellulose, Hydroxypropylcellulose (low substituted), Calcium carbonate, Magnesium stearate, Ferric oxide yellow (E172).

Side Effects of Spedra Tablets

Common Side Effects (may affect up to 1 in 10 people)

  • Headache
  • Skin Flushing
  • Nasal congestion

Uncommon Side Effects (may affect up to 1 in 100 people)

  • Feeling dizzy
  • Feeling sleepy or very tired
  • Sinus congestion
  • Back pain
  • Hot flush
  • Feeling out of breath when exerting yourself
  • Changes in heartbeat seen on an ECG
  • Increased heart rate
  • Feeling heartbeats (palpitations)
  • Indigestion or feeling sick
  • Blurry vision
  • Raised liver enzymes

Serious Side Effects (may affect up to 1 in 1,000 people)

  • Erection lasting more than 4 hours (priapism) which requires immediate treatment
  • Blurred vision
  • Sudden decrease or loss of vision in one or both eyes
  • Sudden decrease or loss of hearing, possibly with dizziness and ringing in the ears

If you experience any side effects, including those not listed, or if any side effects become serious, stop taking Spedra and seek immediate medical advice from your GP or pharmacist. Always read the patient information leaflet for a full list of side effects.

Spedra Warnings

  • Keep out of the SIGHT and REACH of children
  • Spedra does not require any special storage conditions.

Alternatives to Spedra

  • Cialis: Branded tadalafil, effective for up to 36 hours, allowing more spontaneity.
  • Sildenafil: Branded Viagra, effective for 4-6 hours, often used as a first-line treatment.
  • Tadalafil: Available as a daily tablet for those who prefer not to plan intercourse around medication timings.
  • Viagra: Well-known for treating erectile dysfunction, effective within 30-60 minutes and lasts for about 4-6 hours.

Spedra FAQs


Spedra can work for 4 to 6 hours, so you should take it about 30 minutes before sexual activity. Remember, it needs sexual stimulation to be effective.

No, do not take Spedra more than once a day.

Drinking alcohol can increase your heart rate, lower your blood pressure, and reduce your ability to get an erection, so it’s best to avoid it.

Individual responses vary, but Spedra might have a different side effect profile due to its selective action. Consult with your GP or pharmacist for personalised advice.

No, do not use Spedra with other erectile dysfunction treatments like Sildenafil, Tadalafil, or Viagra.

Yes, Spedra can be taken with or without food. However, a heavy meal might delay its effect, so it’s best to take it on an empty stomach.

No, Spedra requires a prescription in the UK. You must consult a GP or pharmacist.

Spedra and Viagra both have similar durations of action, typically 4 to 6 hours. However, individual responses can vary.

Spedra can start working as quickly as 15 to 30 minutes after taking it.

No, there’s no difference between Spedra and Avanfil tablets. Avanafil is the active ingredient in Spedra.

The benefits include a rapid onset of action, with the potential for less planning and more spontaneity in sexual activity.

The main difference lies in their active ingredients—Spedra contains avanafil, while Viagra contains sildenafil. They may also differ in onset time, with Spedra potentially working faster.

Do not take Spedra with the following medicines:

  • Nitrates for chest pain, such as amyl nitrite or glyceryl trinitrate, can severely lower your blood pressure.
  • Medicines for HIV or AIDS like ritonavir, indinavir, saquinavir, nelfinavir, or atazanavir.
  • Medicines for fungal infections, such as ketoconazole, itraconazole, or voriconazole, and certain antibiotics for bacterial infections, like clarithromycin or telithromycin.
  • Other treatments for erectile dysfunction including sildenafil, tadalafil, or vardenafil.
  • Alpha-blockers for prostate problems or high blood pressure.
  • Medicines for irregular heartbeat like quinidine, procainamide, amiodarone, or sotalol.
  • Certain antibiotics for infections, such as erythromycin.
  • Medications for epilepsy or mood stabilisation like phenobarbital, primidone, or carbamazepine.
  • Moderate CYP3A4 inhibitors, which can reduce the breakdown of Spedra in the body, including amprenavir, aprepitant, diltiazem, fluconazole, fosamprenavir, and verapamil.
  • Riociguat used to treat pulmonary arterial hypertension.

Do not take Spedra if:

  • You’re taking specific fungal or bacterial infection treatments.
  • You have severe heart, liver, or kidney issues.
  • You’ve had a stroke or heart attack recently.
  • You have uncontrolled high or low blood pressure.
  • You experience chest pain during sex.
  • You have certain eye problems, like a loss of vision from insufficient blood supply or genetic conditions like retinitis pigmentosa.
  • You’re taking riociguat for lung hypertension.

Talk to your GP or pharmacist before taking Spedra if:

  • You have heart conditions, and sexual activity might be risky.
  • You’ve experienced a persistent erection or have a condition that could cause this.
  • Your penis shape is affected by conditions like Peyronie’s disease.
  • You have a bleeding disorder or an active stomach ulcer.

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