From £31.99
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Pharmacy, clinic and prescribers based in Greater Manchester.
Start your treatment with a quick and free online consultation.
This is a prescription product.You need to complete a consultation form and allow our pharmacists to access your NHS records for review before we can issue this treatment.
Variety of delivery options including next day & free delivery.
Pharmacy, clinic and prescribers based in Greater Manchester.
Start your treatment with a quick and free online consultation.
Fill in a quick online consultation for our licensed pharmacists to review.
Our pharmacists will review your treatment to ensure it’s suitable.
Your treatment will be delivered to your door quickly & discretely.
Epiduo gel is a topical prescription-only medication for treating mild to moderate to severe acne. It contains two active ingredients: adapalene and benzoyl peroxide. It is available in two strengths: Epiduo 0.1%/0.25% and Epiduo Forte 0.3/0.25%. These ingredients work together to clear your skin and prevent future breakouts.
If you’ve tried various over-the-counter acne treatments without success, Epiduo could be the solution you’re looking for. It’s a stronger option that targets multiple causes of acne, offering a universal approach to clearer skin.
| Medication Name | Epiduo Gel |
| Active Ingredient | adapalene and benzoyl peroxide |
| Medication form | Gel |
| Used to treat | Mild to Moderate |
| Available dosages | Epiduo 0.1%/0.25% gel Epiduo 0.3%/0.25% gel |
| Other names by which this medication is known | Epiduo Acne Gel Epiduo Gel |
| Common side effects | Itching, peeling, or burning skin Redness of the skin |
| Who is this medication suitable for | Adults Children over 9 years |
| Do you need a prescription for it? | Yes |
| How should it be used? | Apply a thin film of gel to whole of affected area daily. |
| Patient Information Leaflet | Epiduo Patient Information Leaflet |
Epiduo is primarily used to treat moderate to severe acne symptoms, including different types of acne, like pimples, blackheads, and whiteheads. It’s a go-to treatment for those who need something stronger than standard over-the-counter options.
Epiduo can be used by adults and is designed to work on all skin types, but it is particularly effective for oily skin.
Do not use Epiduo to treat your acne if:
If you have other skin conditions like eczema, consult a GP or pharmacist before starting treatment, as this can dry out the skin.
Epiduo contains adapalene and benzoyl peroxide. Adapalene helps your skin renew itself and unclog pores. Benzoyl peroxide kills acne-causing bacteria and has a mild drying effect, washing away excess oils and dirt.
Results can vary, but you may start to see improvement in your acne in as little as two weeks. However, it’s common to experience the full benefits after up to three months of regular use.
Follow this step-by-step guide on how to apply Epiduo gel:
It’s best to apply the gel at night as it can make your skin more sensitive to the sun, so avoid excess exposure to sunlight or UV lamps. Make sure your skin is clean and dry before application.
Like all acne medications, Epiduo gel can cause side effects.
The side effects below affect between 1% and 10% of people:
You can minimise these side effects by using a non-comedogenic moisturiser and reducing the frequency of applying Epiduo gel until the skin becomes used to the medicine. Within the initial 4 weeks of use, you may experience skin purging, where the skin looks worse before it starts to look better. Skin purging is part of the process of renewing skin cells.
If you experience any of these side effects, you should stop using Epiduo prescription gel immediately and seek medical help:
Please read the patient information leaflet for a full list of side effects.
Active ingredients: adapalene and benzoyl peroxide
Inactive ingredients: docusate sodium, disodium edetate, glycerin, poloxamer, propylene glycerol (E1520), simulgel 600 PHA (copolymer of acrylamide and sodium acryloyldimethyltaurate, isohexadecane, polysorbate 80, sorbitan oleate) & purified water.
Differin is an effective acne treatment that contains adapalene, a powerful retinoid that regulates skin cell turnover. While similar to Epiduo, Differin is a single-ingredient treatment that may be suitable if your skin is sensitive to benzoyl peroxide. It’s particularly good for those just starting acne treatment.
Duac is another benzoyl peroxide gel that combines with the antibiotic clindamycin for a dual-action approach to fighting acne. It works by killing acne-causing bacteria while helping to unclog pores. This can be a good alternative if you need additional antibacterial action in your treatment.
Finacea Gel contains azelaic acid, a gentler alternative that’s especially effective for treating mild to moderate acne. It’s known for reducing inflammation and redness while being suitable for sensitive skin types. Many people find it helpful for treating both active acne and post-acne marks.
If you’ve been struggling with acne and think Epiduo could be your way to clearer skin, don’t wait any longer. You can buy Epiduo online from Click2Pharmacy’s acne treatment clinic as part of our prescription-based service. Start by completing an online assessment right on our website. You’ll then have a consultation with a qualified pharmacist who will determine if Epiduo is the right treatment for you. Once this is approved, it will be delivered discretely to your door.
Epiduo gel is clinically proven to treat mild to moderate acne if you have mostly whiteheads and blackheads with a few papules and pustules. What makes Epiduo gel work so well is that it has two key ingredients that work together to eradicate acne. You can use Epiduo when other single treatments have failed, and it doesn’t contain antibiotics, which is great for people who cannot tolerate them.
Page content authored by Sakib Mohammed, last reviewed by Dr Hussain Ahmad on 30th November 2024.
Epiduo is made by Galderma and contains two active ingredients: adapalene 0.1% and benzoyl peroxide 2.5%.
You may start seeing results in as little as two weeks, but full effects usually take up to three months. Most people notice their skin becoming clearer and smoother after 4-8 weeks of consistent use. Remember that everyone’s skin responds differently, and it’s important to continue using Epiduo even after you start seeing improvements to maintain results.
Yes, but wait until Epiduo has been absorbed into your skin before applying other products. Avoid using other products containing benzoyl peroxide, as this can be too harsh on your skin. Also, steer clear of drying products like alcohol-based toners or harsh exfoliants, as these can increase irritation. Stick to gentle, non-comedogenic moisturizers and sunscreen during your Epiduo treatment.
Both Epiduo gel and Duac gel contain benzoyl peroxide, but Duac contains the antibiotic clindamycin. Both products effectively treat acne, but for people who cannot tolerate antibiotics, Epiduo gel may be a better option.
For long-term safety, it’s best to consult a GP or pharmacist. They can provide guidance based on your skin’s response to the treatment.
Epiduo medication is NOT safe for use in pregnancy. As the effects of Epiduo on breast milk are unknown, it is NOT recommended for breastfeeding. If you find you are pregnant whilst using Epiduo gel, you should stop use immediately.
No, Epiduo requires a prescription in the UK. However, you can get this acne treatment online through our licensed acne treatment clinic after completing a short consultation. This ensures the treatment is safe and suitable for your specific needs.
When you start using Epiduo, apply it once daily, preferably in the evening. Start by applying a thin layer of Epiduo gel to clean dry skin. Some doctors may recommend starting every other day if you have sensitive skin, then gradually increasing to daily use as your skin adjusts.
The ingredients in Epiduo, particularly adapalene, make it effective for treating both active breakouts and new acne scars. While primarily designed to fight acne, the medication’s ability to boost skin cell turnover helps fade recent post-acne marks. However, keep in mind that it’s most effective on newer scarring rather than older, deeper scars.
It’s normal to experience a temporary increase in symptoms of acne when starting Epiduo. This “purging” period occurs as the medication brings existing blockages to the surface, but don’t worry, this means the treatment is working to get rid of underlying acne. This phase typically lasts 4-6 weeks.
