From £21.75
Variety of delivery options including next day & free delivery.
Pharmacy, clinic and prescribers based in Greater Manchester.
Start your treatment with a quick and free online consultation.
This is a prescription product.You need to complete a consultation form and allow our pharmacists to access your NHS records for review before we can issue this treatment.
Variety of delivery options including next day & free delivery.
Pharmacy, clinic and prescribers based in Greater Manchester.
Start your treatment with a quick and free online consultation.
Fill in a quick online consultation for our licensed pharmacists to review.
Our pharmacists will review your treatment to ensure it’s suitable.
Your treatment will be delivered to your door quickly & discreetly.
Duac Gel is a topical antibiotic gel, containing benzoyl peroxide and clindamycin, designed to treat mild to moderate acne. If you are looking for an effective treatment to combat acne and don’t like taking oral antibiotics, Duac acne gel may be the answer. Duac Gel targets the bacteria that cause acne and comes in two strengths: Duac 5% and Duac 3% gel. Each comes in two pack sizes – 30g and 60g. You can buy Duac once daily gel from our online acne treatment clinic.
| Medication Name | Duac Gel |
| Active Ingredients | Clindamycin and hydrous benzoyl peroxide |
| Other Ingredients | Carbomer 940, dimeticone, disodium lauryl sulfosuccinate, disodium edetate, glycerol, silica (colloidal hydrated), poloxamer 182, purified water and sodium hydroxide |
| Medication form | Gel |
| Used to treat | Mild to Moderate |
| Available dosages | 3% 5% in 30g and 60g tubes |
| Other names by which this medication is known | Duac Acne Gel Duac spot treatment |
| Common side effects | Itching, peeling, or burning skin Redness of the skin |
| Who is this medication suitable for | Adults Children over 12 years |
| Do you need a prescription for it? | Yes |
| How should it be used? | Apply once a day at night |
| Patient Information Leaflet | Duac Gel Patient Information Leaflet |
Duac Gel is used to treat mild to moderate acne, including spots, pimples, blackheads, and whiteheads. It belongs to a group of medicines known as ‘anti-acne preparations’. Duac Gel is applied directly onto the skin once daily and has proven an effective treatment for many acne sufferers where other treatments haven’t cleared their spots.
Duac acne treatment can be used by adults and children over the age of 12 years. It may not be suitable for you if you are allergic to clindamycin, benzoyl peroxide or any of the other ingredients below. You should check with your doctor or pharmacist before using this medicine if you have ever had any of the following gut problems: ‘regional enteritis’, ‘ulcerative colitis’, or ‘antibiotic-associated colitis’.
Duac acne gel contains the active ingredients clindamycin and benzoyl peroxide. Clindamycin is an antibiotic that prevents bacteria from reproducing and controls the inflammation of the skin. Benzoyl Peroxide kills bacteria and reduces the number of whiteheads and blackheads by causing the top layer of skin to break down and shed. When used together in Duac spot treatment, they work to fight bacteria causing acne, treat existing blackheads, whiteheads and spots and lower the number of red, inflamed acne spots.
The majority of Duac Gel users find it to be a very effective spot treatment with fast-acting results. Studies show that when using Duac Gel for acne, it works within 2 days of use, quicker than other medicines. You can read more about real patient experiences using Duac Gel here.
Duac Gel can start to treat acne in as little as 48 hours after your first application. However, most patients find it takes between 2 and 6 weeks before you see a noticeable improvement. You should not use Duac Gel for more than 12 weeks unless you have been advised otherwise by your doctor or pharmacist.
You should apply Duac Gel once per day, ideally in the evening. Avoid applying it on the eyes, mouth and inside your nose. If you do accidentally apply Duac Gel to these areas, rinse immediately with plenty of water. Do not apply it to broken, sunburnt or eczema skin. Duac Gel contains benzoyl peroxide, which has bleaching properties, so ensure you wash your hands directly after use and avoid coming into contact with fabrics during application.
When applying Duac Gel, follow these steps for the best results:
Take care not to apply too much Duac Gel as this may cause skin irritation. For your face only, use a ‘finger tips’ amount. If applying to your face and back, use two and a half ‘finger tips’ in total. If you find the gel does not rub into your skin easily, you are likely using too much. If you accidentally apply too much, stop using Duac Gel for a few days until the side effects clear and then resume treatment.
If you forget to use Duac Gel, do not double dose and apply the next dose at the usual time.
Common side effects of Duac acne gel are:
These side effects tend to be mild. If you notice any of the above side effects, try using Duac Once Daily Gel less often.
Uncommon side effects of Duac Gel include:
In rare cases, Duac Gel can cause stomach cramps and diarrhoea as it contains an antibiotic. If you experience any severe side effects, you must stop using Duac acne gel and speak to your doctor or pharmacist.
For a full list of side effects, please read the patient information leaflet.
Active Ingredients: Benzoyl Peroxide 3% or 5% and Clindamycin 1 %
Other Ingredients: Carbomer, dimeticone, disodium lauryl sulfosuccinate, disodium edetate, glycerol, silica, colloidal hydrated, poloxamer 182, purified water and sodium hydroxide.
You can buy Duac online from our online acne treatment clinic as part of our prescription-based service. Simply fill in a consultation form for our prescribing pharmacists to review and ensure Duac Gel is suitable for you. Once approved, your acne treatment will be delivered discretely to your door.
Duac spot gel has two strengths: benzoyl peroxide 3%, clindamycin 1% and benzoyl peroxide 5%, clindamycin 1%. There are two pack sizes of each strength: Duac 30g gel and Duac 60g gel.
Duac 5% gel is a dual-action medicine that fights bacteria causing acne. Clindamycin is an antibiotic that stops bacteria from growing, and benzoyl peroxide kills bacteria. As a result, most people see an improvement in their skin within 30 days.
Duac gel can be used to treat moderate acne where there is inflammation of the skin. Cystic acne is a severe form of acne and so may require another form of treatment.
Yes, Duac once daily gel can be used for back acne. Duac is applied directly onto the skin.
A thin layer of Duac gel should be applied to the entire affected area of the skin, not just individual spots. For example, if applying to the face, you should use a fingertip amount of Duac.
Acne caused by hormonal imbalances can be treated with Duac acne gel. However, contraceptive medication is also an option to restore hormonal balance and can be used alongside other topical products.
Benzoyl peroxide can help with inflammation of the skin in rosacea. Your doctor or pharmacist can advise you if Duac gel is suitable for you.
Duac acne cream is not available. It comes in an easy to apply gel formulation.
There is limited information about the safety of using Duac Once Daily Gel when pregnant. For this reason, we do not recommend if for pregnant women.
Clindamycin, one of the medicines in Duac Gel, may pass into breast milk when taken by mouth or injection. Therefore, it is not safe to apply to your breasts if you are breastfeeding. It is unknown if Duac Gel’s ingredients can be passed into the mother’s milk when applying topically to other areas, so we do not recommended it for breastfeeding mothers.
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.
Do not store Duac Gel in temperatures over 25°C. You should discard Duac Gel two months after you have opened it, or if it has passed it’s expiry date, which is printed on the tube and carton.
Duac acne gel contains 2 ingredients combatting acne in different ways. It contains an acne fighting antibiotic and also another ingredient which is known to reduce bacteria by up to 95%. Duac topical gel is an easy to use product and only needs to be applied once a day. Consistency is key and you may see results in as little as 2 weeks.
Dr Hussain Ahmad
Page content authored by Amjad Khan, last reviewed by Mr Mohammed on 8th July 2025.
