Aknemycin Plus 25ml


Key Features:

  • Topical antibacterial Acne treatment
  • Mild to moderate acne
  • Ideal for acne with oily skin
  • Supplied by UK, NHS registered Pharmacy
  • FREE consultation

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Aknemycin Plus Solution - A view from our expert

Sakib Mohammed

Sakib Mohammed

Advance Pharmacist Prescriber

"Aknemycin Plus is a fantastic product that can tackle acne head-on. It contains 2 ingredients used to treat both inflamed and non-inflamed acne. The antibiotic side kills of the bacteria responsible for acne and the retinoid-based ingredient increases cell turn over which promotes healing and also helps with mild scarring”

Aknemycin information

Key Facts:

Here’s the key information you need to know about Aknemycin plus solution, a medication used to treat inflamed and non-inflamed acne

Medication NameAknemycin Plus
Active Ingredient40 mg of erythromycin and 0.25 mg of tretinoin.
Medication formSolution
Used to treatMild to Moderate Acne
Available dosages40mg/0.25mg
Other names by which this medication is knownAknemycin Plus Solution
Aknemycin Plus 4.0% w/w and 0.025% w/w cutaneous solution
Common side effects
Dry skin
Skin exfoliation (peeling)
Skin burning sensation
Who is this medication suitable forAdults
Children over 12 years
Do you need a prescription for it?Yes
How should it be used?To be applied to the affected areas once or twice daily.
Treatment should continue for 9-12 weeks
Patient Information LeafletAknemycin Plus Patient Information Leaflet

What is Aknemycin and what is it used for?

Aknemycin or Aknemycin Plus is an effective topical antibiotic that helps to reduce the number of spots and pimples caused by acne and treats skin infections. Apart from regular acne, the solution also works on comedones, papules and pustules. Aknemycin Plus is recommended for mild to moderate acne. Please note that Aknemycin Plus is a prescription-only medicine available from the online clinic at Click2Pharmacy.

Who is Aknemycin suitable for?

Aknemycin is suitable for adults over the age of 16 years.

How does Aknemycin Plus work?

The two most effective components, erythromycin and tretinoin, make Aknemycin Plus a potent medicine for treating acne. Erythromycin is an antibiotic that prohibits the growth of bacteria and reduces the number of infected pimples. Tretinoin is a form of vitamin A that exfoliates the skin and unclogs the pores. This action helps to diminish spots caused by acne. Additionally, the alcohol-based formula dissolves away excessive oil and reduces inflammation on the skin.

How long does Aknemycin take to work?

Aknemycin needs to be used until the acne condition improves. A complete treatment course is between 9-12 weeks, but you should start to see your skin improve after the first few weeks. Initially, you may experience some irritation and soreness in your skin. If you are concerned about using Aknemycin Plus, you can speak to one of our pharmacists, who will be happy to advise you.

Alternatives to Aknemycin

There are several products available from Click2Pharmacy, however Epiduo gel is the only one that also contains a retinoid. It also contains another ingredient that kills bacteria For further information:
How to use Aknemycin Plus 25ml Clean your face with a mild cleanser and pat the skin dry. Apply Aknemycin Plus 25ml thinly on the affected skin. Do not apply to sunburnt or sensitive areas or on skin affected by eczema, dermatitis, and rosacea. Keep your eyes, mouth, and nose away from the solution. Use it once or twice as per the direction of your doctor. Do not apply cosmetic products or moisturisers until the solution gets absorbed into the skin.

Aknemycin plus Ingredients

Active Ingredients: Erythromycin-zinc complex containing the equivalent of 40 mg/ml erythromycin and 12 mg/ml zinc acetate dihydrate.

Other ingredients: ethanol, glycerol and copolyvidone.

Aknemycin warnings

After using Aknemycin Plus Solution 25ml, if you experience a severe allergic reaction such as difficulty breathing, seek immediate medical help. As Aknemycin plus can cause the skin to be more sensitive to UV light, it is recommended to wear sunscreen when outdoors and avoid using sunbeds and sunlamps.

Can I use Aknemycin Plus Solution when pregnant or breastfeeding?

Aknemycin Plus should not be used by pregnant women or women trying to get pregnant or breastfeeding women. If you are pregnant or breastfeeding, you must consult the doctor before using the product.   

What are the side effects of Aknemycin Plus?

Not everyone will experience side effects after applying Aknemycin Plus. However, common side effects are:
  • Dry skin,
  • peeling skin,
  • burning, or stinging sensation,
  • feeling a warm sensation on the applied area,
  • skin redness,
  • itchiness,
  • rash,
  • a temporary change in skin complexion,
  • skin crusting
Dryness and redness are the common side effects that improve within a few weeks. Apply a non-oily moisturizer to overcome dryness. For any severe irritation such as scaly red rash, blisters or bumps under the skin, or an allergic reaction, stop using the product and speak to a doctor immediately. For External Use Only Keep out of the REACH and SIGHT of children

Does Aknemycin Plus help with wrinkles and acne?

Yes, Aknemycin Plus can work on wrinkles as it contains tretinoin. Tretinoin is a retinoid used to treat the signs of aging by increasing cell turnover, improving the skin’s elasticity and collagen stores. Over time these effects can reduce wrinkles.

Why do I need a prescription for Aknemycin in the UK?

As Aknemycin is a drug that cannot be taken with other medications, a doctor or qualified health professional must check if you are suitable to use it. A prescription must be issued before you can buy Aknemycin.

Can Aknemycin Plus be used to treat bacterial infections on the skin?

It is common to use Aknemycin Plus to treat bacterial infections on the skin.

What happens if I miss a dose of Aknemycin?

If you notice you have missed a dose of Aknemycin, you should use the product as soon as you remember. However, you should not use extra amounts of the product to make up for missed doses.

Can I buy Akne mycin cream?

Aknemycin Plus is a topical solution. There is a product called erythromycin ointment, a topical antibiotic used to treat acne.

Is it okay to use Aknemycin when breastfeeding?

You cannot use Aknemycin when breastfeeding as the active ingredients can affect breast milk. Please speak to one of our pharmacists for suitable alternatives.


We are regulated by the General Pharmaceutical Council

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