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Sleep Aid 50mg Tablets contain diphenhydramine hydrochloride 50mg, a sedating antihistamine used for the short-term relief of temporary sleeping difficulties.
Diphenhydramine can help you feel drowsy when temporary sleeplessness is making it difficult to get to sleep. It is intended for short-term use only in adults and young people aged 16 years and over.
Please note: Brands and packaging may vary depending on availability. The product supplied will contain diphenhydramine hydrochloride 50mg unless otherwise stated.
Sleep Aid 50mg Tablets are used for the temporary relief of:
They are designed for occasional, short-term use rather than the treatment of ongoing or long-term insomnia.
The active ingredient, diphenhydramine hydrochloride, is a sedating antihistamine.
Diphenhydramine causes drowsiness, which can help you fall asleep when experiencing temporary sleeping difficulties.
Adults and young people aged 16 years and over:
Take one 50mg tablet with water approximately 20 minutes before going to bed.
Do not take Sleep Aid 50mg Tablets if you:
Speak to your doctor or pharmacist before taking diphenhydramine if you have:
Extra caution may be required in older people, particularly where confusion is present.
Do not drink alcohol while taking diphenhydramine, as alcohol can increase its sedative effects.
Diphenhydramine can cause significant drowsiness and may also cause dizziness, blurred vision or difficulty concentrating.
Do not drive, cycle or operate machinery if you are affected.
Speak to your pharmacist or doctor before taking Sleep Aid 50mg Tablets if you use other medicines, particularly:
Avoid taking another medicine containing diphenhydramine at the same time.
If you are pregnant, trying to become pregnant or breastfeeding, speak to your doctor or pharmacist before taking diphenhydramine.
Like all medicines, diphenhydramine can cause side effects, although not everyone experiences them.
Common effects can include:
Stop taking the medicine and seek medical advice if you experience a significant or unexpected reaction.
Always read the patient information leaflet supplied with your medicine for a complete list of warnings and possible side effects.
Diphenhydramine is intended for short-term use.
Regular or prolonged use can result in the medicine becoming less effective and may increase the risk of dependence.
If you continue to experience sleeping difficulties or need to use a sleep aid for longer than 2 weeks, speak to your GP or pharmacist.
The brand, manufacturer, tablet appearance and packaging may vary depending on stock availability.
Where an alternative brand is supplied, check the packaging and patient information leaflet before use and follow the instructions provided with your medicine.
The active ingredient is diphenhydramine hydrochloride 50mg, a sedating antihistamine used for temporary sleeping difficulties.
The usual dose is taken approximately 20 minutes before bedtime.
For a 50mg product, the usual dose for adults and those aged 16 years and over is one tablet before bedtime. Do not exceed the dose stated on your product packaging or leaflet.
No. Diphenhydramine 50mg sleep aid tablets should not be used to help children under 16 years old sleep.
No. Alcohol can significantly increase the drowsiness caused by diphenhydramine and should be avoided.
Diphenhydramine is intended to make you drowsy. Do not drive, cycle or operate machinery if you are sleepy, dizzy, have blurred vision or are unable to concentrate properly.
It is designed for temporary sleeping difficulties and should not be used continuously for more than 2 weeks without medical advice.
Dependence can occur when diphenhydramine is taken for too long without a break. It should therefore only be used for a short period and according to the instructions supplied.
We may supply different licensed brands depending on availability. Brands and packaging may vary, so always check the product label and enclosed patient information leaflet before use.
Page content authored by Dr Hussain Ahmad, last reviewed by Mr Mohammed on 22nd September 2026.
