Orders placed over bank holiday will be processed Tuesday 28th May 2024

Orlistat 120mg Tablets (84)


Complete assessment to buy online.

Continue to assessment
  • Clinically effective weight loss treatment
  • 84 Tablets = 1 month supply
  • Prescription-only medication
  • Multi Buy Options

Orlistat 120mg Tablets 

1 x 84 tablets | £39.99

2 x 84 tablets | £74.98

3 x 84 tablets | £109.95

Having trouble? Send us a message on WhatsApp!

Message us on Whatsapp

Orlistat Tablets for Weight Loss

A view from our expert
Picture Of Sakib Mohammed
Sakib Mohammed

Advance Pharmacist Prescriber

"Orlistat tablets have one main ingredient that contributes to weight loss. It contains a fat-blocking agent that prevents about a third of the fat you eat from being absorbed by your body. Orlistat is simple to use, taken up to three times a day with meals containing fat. Consistency is important, and you may start to see its effects on your digestion within one to two days".

Orlistat Tablets Information

Buy Orlistat Online

Orlistat tablets are a safe and clinically effective prescription weight loss treatment that works by blocking the absorption of fat in your body. When taken with a low-calorie diet and exercise, patients can expect to lose a significant amount of weight. It is suitable for those whose BMI is over 30. 

Orlistat is found in Orlistat, alli and Xenical, which are all weight loss medications.

You can buy Orlistat 120mg tablets for weight loss online through Click2Pharmacy’s online weight loss treatment clinic. We are a licensed online pharmacy, making it easy for you to get the medication you need. Just complete an online consultation for our pharmacists to review, and your prescription will be sent directly to your door.

Orlistat Tablets
Active Ingredient Orlistat
Medication FormTablet
Used to TreatWeight Loss
Available Dosages60mg (OTC), 120mg (Prescription)
Other NamesAlli (OTC), Xenical (Prescription)
Common Side EffectsOily stools, gas, stomach pain
Who is Suitable for This MedicationAdults with:
– BMI of 30 or more (obesity)
– BMI of 27 or more (overweight) with other health issues like high blood pressure or diabetes

Do you Need a Prescription? Yes for 120mg, No for 60mg (Alli)
How Should It Be Used? One Orlistat tablet with each main meal containing fat, up to 3 times a day.

How does Orlistat work?

Orlistat’s main ingredient targets enzymes in your gut that break down fat. When you take the tablet with a meal, it blocks these enzymes and the absorption of fat in your intestines. This means about a third of the fat you eat isn’t broken down, and the undigested fat is passed out through your stools. This helps you take in fewer calories from fat, making it easier to lose weight.

You will see better results if Orlistat is taken when you follow a low-fat, low-calorie diet and exercise regularly. 

How long does Orlistat take to work?

Orlistat capsules work by preventing the absorption of dietary fats. The weight loss medication starts to affect how you digest fat within one to two days, and you will feel the effects of Orlistat on your body and starting weight within a day or two.  Those who take Orlistat should not expect to see any significant weight loss in the first few days of taking it.

Who can take Orlistat tablets? 

Orlistat will usually only be recommended if you’ve made a significant effort to lose weight through diet, exercise or lifestyle changes.

Even then, orlistat is only prescribed if you have either:

  • A body mass index (BMI) of 28 or more, and other weight-related conditions, such as high blood pressure or type 2 diabetes
  • A BMI of 30 or more.

How to take Orlistat Tablets 

The correct dose of Orlistat 120 mg is usually one tablet taken with each main meal that contains fat up to three times a day.

To take Orlistat, follow these steps:

  1. Take one tablet with each main meal that contains some fat. Don’t take more than three tablets a day.
  2. You can take the tablet during the meal or up to one hour after eating.
  3. If a meal has no fat or you skip it, skip the Orlistat dose for that meal.
  4. Keep track of your daily fat, protein, and carb intake. Spread it evenly across your meals.
  5. Stick to a low-calorie diet and exercise regularly for the best results.
  6. Orlistat can affect how your body absorbs some vitamins. You might need to take a vitamin supplement. If so, take it at bedtime or at least two hours before or after taking Orlistat.

How effective is Orlistat?

Orlistat has been shown to effectively lower body weight, BMI, cholesterol levels, and waist circumference. It can also lead to a modest decrease in blood pressure and improved blood sugar control in people with diabetes.

Side Effects of Orlistat Tablets 

Like any medication, when taking Orlistat, you may experience some side effects: 

Common side effects

  • Oily spotting
  • Gas with leaky bowel movements
  • Fecal urgency
  • Fatty or oily stool
  • Increased defecation
  • Abdominal pain or discomfort

Rare side effects

  • Tightness in the chest
  • Tooth or gum problems
  • Troubled breathing
  • Wheezing
  • Bloody or cloudy urine
  • Change in hearing

While certain side effects may be uncomfortable, they can serve as a motivation to adhere to a low-fat diet, enhancing the effectiveness of your weight loss journey.

Should you encounter any severe or unusual side effects from taking Orlistat, seek immediate medical attention.

Orlistat 120mg Capsules Ingredients 

Active Ingredient: Orlistat

Other Ingredients: Microcrystalline cellulose, Sodium starch glycolate, Sodium lauryl sulfate, Povidone and Talc

Orlistat Tablets Warnings 

  • Store the tablets at room temperature, away from moisture and heat.
  • Keep out of the SIGHT and REACH of children
  • If are using the contraceptive pill, it is advisable to use additional protection, such as condoms, as any diarrhoea may impair absorption and increase the risk of pregnancy
  • Orlistat is not suitable if you are breast-feeding

Alternatives to Orlistat 

Orlistat vs. Clavitanol 

Clavitanol is a plant-based weight loss medication available over the counter in the UK. It targets carbs, sugars, and fats. Orlistat is a synthetic weight loss treatment focusing on blocking fat absorption and requires a prescription in the UK. Both have clinical backing for their effectiveness in weight loss but come with different side effects. 

Orlistat vs. Wegovy 

Wegovy is a weight loss injection medication, compared to Orlistat, which is taken in tablet form. Wegovy works by mimicking a hormone that controls appetite, making you feel fuller for longer. Orlistat, on the other hand, blocks the absorption of dietary fats in the intestines. Both medications require a prescription and have their own set of side effects. While Wegovy is often used for more severe cases of obesity, Orlistat is generally used for people who are overweight or obese but may not have as many related health issues.

Our pharmacists can provide advice during the online consultation process to determine the best weight loss medication for your needs and medical history.

Orlistat Weight Loss Tablets FAQs

Orlistat tablets primary use is for treatment to help you lose weight by reducing fat absorption.

Orlistat is usually out of your system within 48 to 72 hours after the last dose. However, the time can vary based on factors like your age, health, and how your liver and kidneys work.

In the UK, you typically need a prescription to buy Orlistat.

A lower-dose version of Orlistat, often sold as Alli, is available over the counter. However, the higher dose usually requires a prescription.

The best time to take Orlistat is with each meal containing fat. You can take it during the meal or up to one hour after eating. If a meal has little or no fat, you can skip the Orlistat dose for that meal.

If you haven’t lost 5% of your body weight after using Orlistat for 3 months, it’s probably not working for you. The drug starts impacting your fat digestion in 1 to 2 days, so if it’s not effective after 3 months, talk to your GP or pharmacist about stopping the treatment.

You can get an Orlistat online prescription through Click2Pharmacy’s online weight medication clinic. Your medication will be sent straight to your door, quickly and discreetly. 

Orlistat Tablets


We are regulated by the General Pharmaceutical Council

Click2Pharmacy Delivery


We offer a variety of delivery options including Next day delivery. Spend over £70 for FREE delivery

Orlistat Tablets


Our pharmacy and clinic is based in Greater Manchester. Our prescibers are in house

Free standard UK delivery

on orders over £70.  Click here for delivery information

Customer Reviews

Based on 68 reviews
Ibrahim Ahsan
Ibrahim Ahsan
Very helpful staff, never had any issues with this pharmacy, 100% recommend
Julie Beardsley
Julie Beardsley
Very professional service. Just like having your very own pharmacist. Brilliant
Mohammed Khan
Mohammed Khan
Just had private bloods taken short wait time very thorough good price nice lady would recommend.
Sarah Smithies
Sarah Smithies
It is great to have somewhere local that does blood testing. The staff are lovely, helpful and experienced. They fit me in last minute. There is never a wait and the results back within a day or two.
After refusal of doctors appointment same old same old ring back etc. I was invited at 5.25 to see doctor I drove over immediately. Everything fully explained and checked over I was leaving by 6pm with penicillin for strep throat. Had I followed my doctors receptionist I would probably have suffered longer and increased the chances of a worse infection.I Great efficient service.
Lisa Lowther
Lisa Lowther
Fantastic service went for blood done very fast very friendly fantastic customer service

Weight Loss Medication Advice