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Esomeprazole 20mg – 28 pack


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Key Features

  • Esomeprazole 20mg is used for treating heartburn, acid reflux, and stomach ulcers.
  • Usually taken once a day, it can be with or without food. Swallow whole with water.
  • Buy online with a prescription from our UK-registered pharmacy.

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Buy Esomeprazole 20mg Online for Acid Reflux

A view from our expert
Picture Of Sakib Mohammed

Sakib Mohammed

Advance Pharmacist Prescriber

“Heartburn, difficulty swallowing, and acid reflux often bring a lot of discomfort and pain to those experiencing these types of symptoms, which is why it’s so positive to see these patients again after they’ve taken Esomeprazole and found it to provide relief. Esomeprazole is a great option for helping aid the healing process when it comes to acid damage to the stomach and esophagus and can help to prevent ulcers. Some studies have even found the drug to be useful in preventing the onset of esophagus cancer.”

About Esomeprazole 20mg Tablets

Esomeprazole 20mg is a type of prescription medication called a Proton Pump Inhibitor, commonly known as a PPI. This medicine works by cutting down the acid in your stomach and easing acid reflux symptoms. It’s a go-to choice for treating issues like heartburn, acid reflux, and even stomach ulcers. Esomeprazole 20mg is available in the UK with a prescription from your GP or pharmacist. 

Key featuresDetails about Esomeprazole 20mg
Drug TypeProton Pump Inhibitor (PPI)
UseTreats acid reflux and ulcers
FormCapsule, tablet
How to takeOrally, Empty Stomach
Common side effectsHeadache, nausea, diarrhea
StorageRoom temp, away from moisture
Prescription NeededYes
InteractionsSome antibiotics, blood thinners
GP or pharmacist adviceDon’t use long-term without advice

What is Esomprazole used for?

Esomeprazole is used to treat conditions related to excess stomach acid, such as: 

Who is Esomeprazole 20mg suitable for?

Most adults can take Esomeprazole if they suffer from acid reflux or gastrointestinal issues. However, children will only be prescribed Esomeprazole if they suffer from GERD. 

Esomeprazole may not be suitable for you if you:

  • have ever had an allergic reaction to esomeprazole or any other medicine
  • have liver problems
  • are due to have an endoscopy

Esomeprazole may hide some of the problems that would usually be spotted during an endoscopy. If you are due to have an endoscopy, ask your doctor if you should stop taking esomeprazole a few weeks before your procedure. 

How does Esomeprazole work?

Esomeprazole works by reducing the acid levels in the stomach by blocking systems in the cell walls of the stomach called Proton Pumps. Esomeprazole helps to prevent proton pumps in the stomach from working properly. These proton pumps are enzymes found in the lining of the stomach which produce acid, thereby decreasing the amount of acid in the stomach. 

How to take Esomeprazole 

Esomeprazole 20mg is typically taken once a day first thing in the morning and swallowed whole with a glass of water . It can be taken either with or without food. 

If you are recommended by your GP or pharmacist to take Esomeprazole twice a day, take one dose in the morning and one dose in the evening. 

What are the Side Effects of Esomeprazole 20mg?

If you experience any of the following side effects from taking Esomeprazole, tell your doctor or pharmacist and seek appropriate advice from them.

Common Side Effects

  • Headache
  • Effects or pain in your stomach or gut
  • Diarrhoea
  • Constipation
  • Feeling sick (nausea) or vomiting
  • Benign polyps in the stomach

Uncommon Side Effects

  • Swelling of the feet and ankles
  • Feeling sleepy or disturbed sleep
  • Dizziness
  • Tingling feelings such as “pins and needles”
  • Spinning feeling (vertigo)
  • Skin rash, hives and itchy skin

Rare Side Effects

  • Eyesight problems such as blurred vision
  • Suddenly feeling wheezy or short of breath (bronchospasm)
  • Thrush 
  • Skin rash on exposure to sunshine
  • Joint pains (arthralgia) or muscle pains (myalgia)

You can find all of the side effects in the Esomeprazole 20mg patient information leaflet

Long-Term Side Effects of Taking Esomeprazole 20mg 

Despite the widespread use and excellent safety profile of Esomeprazole 20mg, concerns have been raised about the long-term effects of proton pump inhibitors. These concerns include potential adverse effects like hypergastrinemia, the development of pneumonia, and drug interactions. The NHS advises that it should be used under medical guidance for the most effective and safest long-term treatment. 

A recent study has also found that long-term use of PPIs, like Esomeprazole, can lead to an increased risk of dementia

If you are unsure whether you will need to take Esomeprazole long-term and are worried about the side effects, talk to your doctor or pharmacist. 

Esomeprazole 20mg Ingredients 

Active Ingredients: Esomeprazole

Inactive ingredients: sugar spheres (sucrose and maise starch), crospovidone, hydroxypropyl cellulose, sodium hydroxide, mannitol, sucrose, methacrylic acid – ethyl acrylate polymer (1:1) dispersion 30%, triethyl citrate, glycerol monostearate, polysorbate 80, talc

Alternatives to Esomeprazole 

If you cannot take Esomeprazole, there are other Proton Pump Inhibitors for acid reflux, heartburn and indigestion available. At Click2Pharmacy, we also stock Lansoprazole, Pantoprazole and Omeprazole, which can be purchased online following a consultation with one of our pharmacists. 

Buy Esomeprazole Online from Click2Pharmacy 

Esomeprazole is an effective option for treating stomach issues like acid reflux and indigestion. You can buy Esomeprazole online by filling in our short online consultation form, which will be reviewed by our licensed pharmacists. At Click2Pharmacy, our regulated online UK-based pharmacy has a dedicated acid reflux clinic. We can help you find the right treatment whilst offering 100% confidentiality with the best online pharmacy prices. Complete our online assessment to buy Esomeprazole online today.

Esomeprazole 20mg FAQs

Yes, you can buy Esomeprazole online from Click2Pharmacy by completing an online assessment as part of our online acid reflux clinic

If you’re pregnant or breastfeeding, it’s best to talk to a GP or pharmacist before taking Esomeprazole 20mg. While it’s generally considered safe, every pregnancy is different, and it’s important to get personalised advice.

Taking Esomeprazole with other medications, like Digoxin or HIV medicines, can sometimes cause interactions. Always let your GP or pharmacist know about other medicines you’re taking.

Esomeprazole is not known to affect the contraceptive pill. However, when filling in an online consultation with our clinic, disclose what contraceptive pill and any other medications you are taking so we can confirm this is the case before issuing your prescription.

Esomeprazole 20Mg


We are regulated by the General Pharmaceutical Council

Esomeprazole 20Mg


We offer a variety of delivery options including Next day delivery. Spend over £70 for FREE delivery.

Esomeprazole 20Mg


Our pharmacy, clinic & prescribers are based in Greater Manchester.

Free standard UK delivery

on orders over £70.  Click here for delivery information

Customer Reviews

Based on 68 reviews
Ibrahim Ahsan
Ibrahim Ahsan
Very helpful staff, never had any issues with this pharmacy, 100% recommend
Julie Beardsley
Julie Beardsley
Very professional service. Just like having your very own pharmacist. Brilliant
Mohammed Khan
Mohammed Khan
Just had private bloods taken short wait time very thorough good price nice lady would recommend.
Sarah Smithies
Sarah Smithies
It is great to have somewhere local that does blood testing. The staff are lovely, helpful and experienced. They fit me in last minute. There is never a wait and the results back within a day or two.
After refusal of doctors appointment same old same old ring back etc. I was invited at 5.25 to see doctor I drove over immediately. Everything fully explained and checked over I was leaving by 6pm with penicillin for strep throat. Had I followed my doctors receptionist I would probably have suffered longer and increased the chances of a worse infection.I Great efficient service.
Lisa Lowther
Lisa Lowther
Fantastic service went for blood done very fast very friendly fantastic customer service