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Home > Online Clinic > Acid Reflux > Alka-Seltzer Original (10,20)

Alka-Seltzer Original (10,20)

  • Alka-Seltzer Original provides fast relief from headache with upset stomach, indigestion, and heartburn.
  • Contains aspirin with antacids (sodium hydrogen carbonate and citric acid) for pain and acid relief.
  • Suitable for adults and children over 16, but may not be right for everyone.
  • Buy online from a licensed UK pharmacy.
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Fast & Free Delivery Options

Variety of delivery options including next day & free delivery.

100% UK-based Pharmacy

Pharmacy, clinic and prescribers based in Greater Manchester.

Free Online Consultations

Start your treatment with a quick and free online consultation.

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Step 2: Choose a Treatment

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About Alka-Seltzer Original

Medication Name Alka-Seltzer Original
Type and Form of Medicine Effervescent tablets
What it Does Relieves headache with upset stomach, heartburn, and indigestion
Active Ingredients Aspirin, sodium hydrogen carbonate, citric acid
Strength Each tablet contains aspirin 324mg, sodium hydrogen carbonate 1,744mg, citric acid 965mg
Size Available in packs of 10 or 20 effervescent tablets
Patient Information Leaflet Click here

What is Alka-Seltzer Original?

Alka-Seltzer Original are effervescent aspirin tablets with added antacid ingredients. They provide quick relief from headache with upset stomach, indigestion, and acid-related discomfort, while also easing pain such as migraine, toothache, period pain, and fever.

What is Alka-Seltzer Original used for?

Alka-Seltzer Original is used for the short-term relief of:

  • Headache with indigestion or upset stomach
  • Heartburn and acid reflux
  • Migraine and toothache
  • Fever, aches, and pains from cold or flu

How does Alka-Seltzer Original work?

Alka-Seltzer Original contains:

  • Aspirin: A pain reliever that reduces pain, fever, and inflammation.
  • Sodium hydrogen carbonate and citric acid: Antacids that neutralise excess stomach acid to ease indigestion and heartburn.

The effervescent form helps the ingredients absorb quickly for fast relief.

Who is Alka-Seltzer Original suitable for?

Alka-Seltzer Original is suitable for adults and children over 16 years old.

It may not be suitable if you:

  • Are allergic to aspirin or other NSAIDs
  • Have stomach ulcers, bleeding problems, or gout
  • Have severe kidney or liver disease
  • Are pregnant or breastfeeding
  • Take anticoagulants (blood thinners) or other aspirin-containing medicines

How to take Alka-Seltzer Original

  1. Dissolve 2 tablets in half a glass of water and drink immediately.
  2. Adults and children over 16: Take 2 tablets every 4 hours as needed.
  3. Do not take more than 8 tablets in 24 hours.
  4. Do not use for more than 3 days without medical advice.

Alka-Seltzer Original Side Effects

Like all medicines, Alka-Seltzer may cause side effects.

Common Side Effects

  • Stomach upset, nausea, or indigestion

Uncommon Side Effects

  • Allergic reactions such as rash or itching
  • Dizziness or ringing in the ears

Serious Side Effects

  • Severe allergic reaction (swelling of face, lips, throat, difficulty breathing)
  • Stomach bleeding (black stools, blood in vomit)
  • Severe abdominal pain

For the full list of side effects, see the patient information leaflet.

Alka-Seltzer Original Ingredients

Active Ingredients: Aspirin 324mg, sodium hydrogen carbonate 1,744mg, citric acid 965mg per tablet.

Other Ingredients: None.

Important Information

  • Not suitable for children under 16 due to risk of Reye’s syndrome.
  • Do not take if you are allergic to aspirin or other NSAIDs.
  • Speak to your doctor before use if you have asthma, kidney, or liver problems.
  • Do not combine with other aspirin, NSAIDs, or blood thinners unless advised.
  • Store out of the sight and reach of children.

Alka-Seltzer Original (10,20) Reviews

FAQs


It relieves headache with upset stomach/indigestion, mild to moderate pain, fever, and cold & flu symptoms, and helps with rheumatic/muscular aches.

Dissolve 2 tablets in ~100 ml water every 4 hours if needed, up to 8 tablets in 24 hours, for no more than 3 days.

Avoid combining with other NSAIDs (like ibuprofen/naproxen) — risk of stomach irritation/bleeding increases. Ask a pharmacist about alternatives (e.g., paracetamol) if extra pain relief is needed.

Do not use if you are pregnant, breast-feeding or trying for a baby unless your doctor tells you to.

No — not for under-16s due to the risk of Reye’s syndrome. Speak to a pharmacist about child-appropriate options.

Yes. Each tablet contains about 477 mg sodium. Seek advice if you’re on a low-sodium diet.

It dissolves to work fast; taking it after food may reduce stomach upset. Follow the label and PIL.

It can relieve headache with upset stomach after a heavy night, but avoid alcohol while taking Alka-Seltzer and don’t exceed the dose/duration limits. If symptoms persist, speak to a pharmacist or GP.

Our Experienced UK-based Pharmacy Team

Clinical Consultant
MUDr, MRCEM, EBCEM, FRCEM
GMC no. 7176414

Pharmacist
MPharm
GPhC no. 2065469

Pharmacist
MPharm
GPhC no. 2046514

Page content authored by Muhammad, last reviewed by Amjad Khan on 15th September 2025.

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