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Variety of delivery options including next day & free delivery.
Pharmacy, clinic and prescribers based in Greater Manchester.
Start your treatment with a quick and free online consultation.
Fill in a quick online consultation for our licensed pharmacists to review.
Our pharmacists will review your treatment to ensure it’s suitable.
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| Medication Name | Alka-Seltzer Original |
| Type and Form of Medicine | Effervescent tablets |
| What it Does | Relieves headache with upset stomach, heartburn, and indigestion |
| Active Ingredients | Aspirin, sodium hydrogen carbonate, citric acid |
| Strength | Each tablet contains aspirin 324mg, sodium hydrogen carbonate 1,744mg, citric acid 965mg |
| Size | Available in packs of 10 or 20 effervescent tablets |
| Patient Information Leaflet | Click here |
Alka-Seltzer Original are effervescent aspirin tablets with added antacid ingredients. They provide quick relief from headache with upset stomach, indigestion, and acid-related discomfort, while also easing pain such as migraine, toothache, period pain, and fever.
Alka-Seltzer Original is used for the short-term relief of:
Alka-Seltzer Original contains:
The effervescent form helps the ingredients absorb quickly for fast relief.
Alka-Seltzer Original is suitable for adults and children over 16 years old.
It may not be suitable if you:
Like all medicines, Alka-Seltzer may cause side effects.
For the full list of side effects, see the patient information leaflet.
Active Ingredients: Aspirin 324mg, sodium hydrogen carbonate 1,744mg, citric acid 965mg per tablet.
Other Ingredients: None.
GOOD Based on 184 reviews Posted on Google Bradley Robinson30/04/2026 Absolutely Amazing staff! Such a help thank you so muchPosted on Google Samiur Rahman30/04/2026 Best pharmacy in the UK. The staff here are very helpful, empathetic, understanding and compassionate. Brilliant customer service and staff are actual people who use their discretion to help people.Posted on Google Vivien donnellon29/04/2026 Extremely efficient and knowledgeable information given. All my questions were answered and also some advise regarding the issue. Thank you RehanaPosted on Google james watkins22/04/2026 Brilliant device ordered yesterday received it today
It relieves headache with upset stomach/indigestion, mild to moderate pain, fever, and cold & flu symptoms, and helps with rheumatic/muscular aches.
Dissolve 2 tablets in ~100 ml water every 4 hours if needed, up to 8 tablets in 24 hours, for no more than 3 days.
Avoid combining with other NSAIDs (like ibuprofen/naproxen) — risk of stomach irritation/bleeding increases. Ask a pharmacist about alternatives (e.g., paracetamol) if extra pain relief is needed.
Do not use if you are pregnant, breast-feeding or trying for a baby unless your doctor tells you to.
No — not for under-16s due to the risk of Reye’s syndrome. Speak to a pharmacist about child-appropriate options.
Yes. Each tablet contains about 477 mg sodium. Seek advice if you’re on a low-sodium diet.
It dissolves to work fast; taking it after food may reduce stomach upset. Follow the label and PIL.
It can relieve headache with upset stomach after a heavy night, but avoid alcohol while taking Alka-Seltzer and don’t exceed the dose/duration limits. If symptoms persist, speak to a pharmacist or GP.
Page content authored by Muhammad, last reviewed by Amjad Khan on 15th September 2025.




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