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Start your treatment with a quick and free online consultation.
Fill in a quick online consultation for our licensed pharmacists to review.
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Nitrofurantoin is an antibiotic primarily used in the form of 100mg modified-release capsules, ensuring a more consistent release of medication. This consistent release is particularly beneficial in providing sustained relief from symptoms and ensuring effective eradication of the infection.
| Medication Name | Nitrofurantoin 100mg Modified Release Capsules |
| Active Ingredient | Nitrofurantoin 100mg (Modified Release) |
| Medication Form | Capsules for oral use |
| Used to Treat | Urinary Tract Infections (UTIs) and bladder infections |
| Available Size | 6 capsules |
| Other Names | Macrobid / Nitrofurantoin MR |
| Common Side Effects | Nausea, loss of appetite, diarrhoea, headache, and dizziness |
| Who is it Suitable For | Adults and elderly patients (not suitable for most children) |
| Do You Need a Prescription? | Yes – prescription only medicine (POM) |
| How Should it Be Used? | Take one capsule every 12 hours (morning and evening) with food, as prescribed by your clinician |
| Patient Information Leaflet | Nitrofurantoin 100mg Modified Release Capsules – Patient Information Leaflet |
Nitrofurantoin antibiotics are primarily used for treating and preventing urinary tract infections (UTIs), such as cystitis. It works effectively by killing the bacteria responsible for these infections. Symptoms of cystitis and UTIs include:
In addition to UTIs, Nitrofurantoin may also be used for other bacterial infections as determined by a doctor or pharmacist.
Nitrofurantoin functions by entering the bacterial cells and interfering with their chemical processes. It inhibits the synthesis of bacterial proteins, DNA, RNA, and cell walls, leading to the bacteria’s death. This stops the infection from spreading, allowing the immune system to eliminate the remaining bacteria.
The usual dose for treating UTIs in adults is either one 50mg or 100mg capsule taken twice a day for 3 days. For the prevention of further infections, a single 100mg capsule at bedtime may be recommended. Dosage may vary based on individual health conditions and the severity of the infection. Follow the prescribed dosage and do not exceed the maximum recommended dose unless advised by a doctor or pharmacist.
Nitrofurantoin antibiotics are suitable for adults and children over three months of age, particularly for those diagnosed with UTIs. However, it may not be appropriate for individuals with:
Pregnant women, especially in the final stages of pregnancy, and breastfeeding mothers should consult their doctor or pharmacist before using Nitrofurantoin.
For treating cystitis, the medication is typically taken for three days. The duration may be adjusted based on the severity of the infection and the individual’s response to treatment.
You can buy Nitrofurantoin 100mg online from our online cystitis treatment clinic by completing a free consultation. Once reviewed by a licensed pharmacist, we will issue your prescription and deliver the medication directly to your door in discrete packaging.
If you experience any severe or concerning side effects, stop using Nitrofurantoin immediately and seek medical attention.
For a complete list of side effects, please read the patient information leaflet.
Reports of long-term side effects include lung and liver damage, especially with prolonged use. Studies indicate these risks increase with extended treatment duration. If concerned about long-term side effects, consult with your GP or pharmacist.
Active Ingredients: Nitrofurantoin.
Other Ingredients: Talc, maize starch, lactose monohydrate, gelatin, sodium lauryl sulfate, quinoline yellow (E104), and titanium dioxide (E171).
The typical dose of Nitrofurantoin antibiotics for treating a urinary tract infection (UTI) in adults is either one 50mg or 100mg capsule taken twice times a day for seven days.
Nitrofurantoin is highly effective for treating cystitis, with success rates in rapidly clearing infections and alleviating symptoms.
Symptoms usually improve within a few days of starting treatment, but it’s important to complete the full course of nitrofurantoin antibiotics.
In the UK, Nitrofurantoin is a prescription-only medication. You can buy Nitrofurantoin online from Click2Pharmacy’s online Cystitis clinic following a free consultation.
Alcohol consumption is not advised as it may increase the risk of liver problems and reduce the effectiveness of the medication.
If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. As far as it is known Nitrofurantoin Capsules may be used in pregnancy.
The duration of treatment typically lasts three days for acute infections, but your doctor or pharmacist may adjust this based on your condition.
Store below 30°C in the original package, away from light and moisture. Do not use after the expiry date.
Inform your pharmacist of all medications you are taking, as Nitrofurantoin may interact with certain drugs. Always disclose your medication history during your online consultation for safety review.
Nitrofurantoin stands out as a first-line treatment for cystitis due to its targeted action against the bacteria causing urinary tract infections. Its effectiveness, combined with a favourable safety profile, makes it a preferred choice for many patients.
Dr Hussain Ahmad
Page content authored by Amjad Khan, last reviewed by Mr Mohammed on 20th October 2025.
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