Home > Online Clinic > Eczema & Dermatitis > HC45 Hydrocortisone Acetate Cream

HC45 Hydrocortisone Acetate Cream

  • Relieves eczema, dermatitis, and insect bites
  • Reduces itching, redness, and swelling fast
  • Soothes skin irritated by metals and chemicals
Fast & Free Delivery Options

Variety of delivery options including next day & free delivery.

100% UK-based Pharmacy

Pharmacy, clinic and prescribers based in Greater Manchester.

Free Online Consultations

Start your treatment with a quick and free online consultation.

1 x item
£5.89
Total:
£5.89
3 x items
Save 4 %
£5.66
Total:
ÂŁ16.98
  • Total

In stock

From £5.66
24 hr tracked delivery once approved
Fast & Free Delivery Options

Variety of delivery options including next day & free delivery.

100% UK-based Pharmacy

Pharmacy, clinic and prescribers based in Greater Manchester.

Free Online Consultations

Start your treatment with a quick and free online consultation.

How to Buy Online

Step 1: Online Consultation

Fill in a quick online consultation for our licensed pharmacists to review.

Step 2: Choose a Treatment

Our pharmacists will review your treatment to ensure it’s suitable.

Step 3: Quick & Discreet Delivery

Your treatment will be delivered to your door quickly & discreetly.

About HC45 Hydrocortisone Acetate Cream

HC45 Hydrocortisone Acetate Cream contains hydrocortisone acetate 1% w/w, a mild corticosteroid used to reduce inflammation and soothe irritated skin. It is specially formulated to provide relief from the symptoms of various skin conditions, including mild to moderate eczema, dermatitis, and allergic reactions to insect bites or stings. By altering the body’s inflammatory response, HC45 helps to calm redness, swelling, and itching for up to 12 hours.HC45 Hydrocortisone Cream is suitable for adults and children aged 10 years and over:

  • HC45 Hydrocortisone Acetate Cream – 15g
Medication Name HC45 Hydrocortisone Acetate Cream
Active Ingredient Hydrocortisone Acetate BP 1.0% w/w
Medication Form Topical Cream
Used to Treat Eczema, dermatitis, insect bites, and skin irritations
Available Sizes 15g tube
Who Can Use It Adults and children aged 10 years and over
Prescription Required? No – Pharmacy (P) medicine
Patient Information Leaflet HC45 Hydrocortisone Cream – Patient Information Leaflet

What Is HC45 Hydrocortisone Cream Used For?

HC45 Cream is used to treat skin inflammation caused by irritant contact dermatitis, allergic contact dermatitis, insect bite reactions, and mild to moderate eczema. It works by suppressing the release of inflammatory chemicals in the skin cells, effectively reducing the “flare-up” symptoms like swelling, redness, and intense itching.

Who Is HC45 Hydrocortisone Cream Suitable For?

HC45 is suitable for adults and children aged 10+. Do not use HC45 Hydrocortisone Cream if you:

  • Are allergic to hydrocortisone acetate or any other listed ingredients
  • Have skin conditions such as acne, rosacea, or perioral dermatitis
  • Have broken skin or skin infections (e.g., impetigo, athlete’s foot, cold sores, or chickenpox)
  • Are treating the eyes, face, or ano-genital area

Speak to a healthcare professional before use if you:

  • Are pregnant or breastfeeding
  • Are treating a child under 10 years of age
  • Require the cream for a large area of the body
  • Have a history of visual disturbances or eye conditions like glaucoma

Ingredients

Other ingredients: White soft paraffin, cetomacrogol emulsifying wax (containing cetostearyl alcohol), liquid paraffin, phenoxyethanol, and purified water.

How to Use HC45 Hydrocortisone Cream

  1. Check that the tube seal is intact before the first use.
  2. Wash your hands before application.
  3. Apply the cream accurately and sparingly to the affected area.
  4. Gently massage the cream into the skin until it disappears.
  5. Wash your hands after use (unless the hands are the area being treated).

Do not cover the treated area with an occlusive dressing (such as a plaster or bandage) unless advised by a doctor. Do not use for more than 7 days.

Possible Side Effects of HC45 Hydrocortisone Cream

Most people use HC45 without issues, but side effects can occur:

  • Not Known: Local skin reactions, thinning of the skin (atrophy), stretch marks (striae), or changes in skin pigmentation.
  • Rare: Blurred vision or other visual disturbances.

Chronic misuse or prolonged use on large areas can lead to systemic steroid effects, such as adrenal suppression.

Warnings and Precautions

  • For external use only.
  • Do not exceed the recommended 7-day treatment period.
  • Avoid contact with eyes and mucous membranes.
  • Contains cetostearyl alcohol, which may cause local skin reactions.
  • Keep away from naked flames; treated fabric/bedding can be a fire hazard.

Storage Instructions

  • Store below 25°C.
  • Do not use after the expiry date stated on the tube.
  • Keep out of the sight and reach of children.

 

HC45 Hydrocortisone Acetate Cream Reviews

Our Experienced UK-based Pharmacy Team

Clinical Consultant
MUDr, MRCEM, EBCEM, FRCEM
GMC no. 7176414

Pharmacist
MPharm
GPhC no. 2065469

Pharmacist
MPharm
GPhC no. 2046514

Page content authored by Amjad Khan, last reviewed by Dr Hussain Ahmad on 16th April 2026.

Get 10% Off Your First Order

Sign up to receive special offers via email and get 10% off your first order*

By opting in to marketing, you agree to our terms & conditions and privacy policy.