From £14.99
Variety of delivery options including next day & free delivery.
Pharmacy, clinic and prescribers based in Greater Manchester.
Start your treatment with a quick and free online consultation.
This is a prescription product.You need to complete a consultation form and allow our pharmacists to access your NHS records for review before we can issue this treatment.
Variety of delivery options including next day & free delivery.
Pharmacy, clinic and prescribers based in Greater Manchester.
Start your treatment with a quick and free online consultation.
Fill in a quick online consultation for our licensed pharmacists to review.
Our pharmacists will review your treatment to ensure it’s suitable.
Your treatment will be delivered to your door quickly & discretely.
| Medication Name | Nystaform HC cream & Nystaform HC ointment |
| Medication Form | Topical cream & topical ointment |
| Used for | Treats skin infections caused by fungi and bacteria |
| Active Ingredients | Nystaform HC cream: nystatin, chlorhexidine hydrochloride, hydrocortisone
Nystaform HC ointment: nystatin, chlorhexidine acetate, hydrocortisone. |
| Size | 30g |
| Patient Information Leaflet | Nystaform HC Cream Patient Information Leaflet Nystaform HC Ointment Patient Information Leaflet |
Nystaform HC cream and Nystaform HC ointment are used to treat skin infections caused by bacteria or fungi (particularly Candida), including:
Both the cream and ointment can reduce symptoms like itching, redness, and discomfort as they contain a mild steroid.
Both Nystaform cream and Nystaform ointment contain three active ingredients which help control the infection and soothe the skin:
| Feature | Nystaform HC Cream | Nystaform HC Ointment |
| Texture | Light, non-greasy | Thicker, greasier |
| Best for | Moist, weepy or inflamed skin | Dry, flaky or rough skin |
| Steroid strength | Hydrocortisone 0.5% (mild steroid) | Hydrocortisone 1% (still mild, but slightly stronger) |
| Antiseptic type | Chlorhexidine hydrochloride | Chlorhexidine acetate |
| Absorption | Absorbs quickly, leaves less residue | Slower to absorb, creates a protective barrier |
| Common uses | Infected nappy rash, moist rashes | Infected eczema, dry patches, fungal infections |
| Skin feel | Suitable for daytime use under clothing | More occlusive — may be better at night |
You should choose Nystaform HC cream if your skin is moist or the infection is in skin folds and you want a quicker-absorbing product.
Nystaform HC ointment might be better if your skin is dry, cracked, or needs more moisture and protection.
If you’re unsure which is best for your condition, your pharmacist or GP can help guide you based on where and how you’re using it.
Nystaform HC cream and ointment can be used by adults and children. However, at Click2Pharmacy, we can only prescribe to adults over 18.
Do not use if you:
Use the cream or ointment for a maximum of 7 days. If a new infection appears, stop using the cream or ointment and speak to your doctor or pharmacist, as an alternative treatment may be needed.
Like all medications, Nystaform HC cream and Nystaform HC ointment can cause side effects. Some possible side effects include:
If you experience any of these side effects, discontinue use and consult your doctor immediately. For a full list of the side effects, please check the Nystaform HC Cream Patient Information Leaflet or the Nystaform HC Ointment Patient Information Leaflet.
Steroid Withdrawal Reaction
In some cases, especially after prolonged or repeated use, stopping treatment with a steroid-containing cream or ointment like Nystaform HC may lead to a withdrawal reaction.
This can cause symptoms that are different from your original condition and may include intense redness that spreads beyond the area originally treated, a burning or stinging sensation, severe itching, peeling skin, and oozing sores. If you notice these symptoms after stopping treatment, speak to your doctor or pharmacist before restarting use.
If you notice any side effects, tell your doctor or pharmacist, even if they are not listed here. You can also report side effects through the Yellow Card Scheme. Reporting helps to improve the understanding of this medication’s safety.
Most people notice improvements within a few days of using Nystaform HC cream or ointment. If your skin is still infected after 7 days, speak to your doctor or pharmacist, as you may need a different treatment.
There’s no known interaction between alcohol and Nystaform HC treatments.
Nystaform HC should not be used during pregnancy or while breastfeeding.
Nystaform HC is a prescription-only medication available from our online ringworm treatment clinic. When you purchase this product, we will ask you to complete a short online consultation to check if it’s suitable. Our pharmacists will review your details and prescribe Nystaform HC if it is appropriate for your condition.
Nystaform cream is not suitable for treating vaginal thrush. For thrush (vaginal candidiasis), you should use a product that is specifically made for internal use, like Canesten internal cream, and you may also need an antifungal capsule like fluconazole. Visit our online thrush treatment clinic to find appropriate medications.
Nystaform HC is not usually used to treat eczema. However, it may be prescribed in certain cases where eczema has become infected with bacteria or fungi. If your eczema is infected (for example, if it’s weeping, crusty, or getting worse despite normal treatment), a doctor might recommend Nystaform HC for short-term use.
Always speak to your GP or pharmacist before using Nystaform HC on eczema, especially in sensitive areas like the face or on children.
For non-infected eczema, a standard steroid cream or emollient is usually more appropriate. Visit our online eczema & dermatitis treatment clinic for alternative medications.
Nystaform HC is a helpful triple-action treatment if your skin is sore, itchy, and infected. It fights bacteria and fungus, reduces redness, and helps your skin heal more quickly.
Dr Hussain Ahmad
Page content authored by Mr Mohammed, last reviewed by Amjad Khan on 17th April 2025.
