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Variety of delivery options including next day & free delivery.
Pharmacy, clinic and prescribers based in Greater Manchester.
Start your treatment with a quick and free online consultation.
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Panadol Night Pain Tablets are a specially formulated dual-action medication designed for the short-term relief of bedtime pain. Combining paracetamol and diphenhydramine hydrochloride, these tablets effectively target aches and pains that prevent you from falling asleep. Whether you are suffering from a persistent headache, backache, or muscle pain, Panadol Night helps reduce discomfort while the antihistamine component aids a restful night’s sleep.
Panadol Night Pain Tablets are suitable for adults and adolescents aged 16 years and over and are available in one pack size:
| Medication Name | Panadol Night Pain Tablets |
| Active Ingredients | Paracetamol 500mg and Diphenhydramine Hydrochloride 25mg |
| Medication Form | Film-coated tablets |
| Used to Treat | Bedtime pain including headaches, migraine, backache, and rheumatic pain |
| Available Sizes | 20-tablet pack |
| Who Can Use It | Adults and children aged 16 years and over |
| Prescription Required? | No – Pharmacy (P) medicine |
| Patient Information Leaflet | Panadol Night – Patient Information Leaflet |
Panadol Night is specifically used for the relief of nighttime pain such as headaches, migraines, backache, rheumatic and muscle pain, toothache, or period pain which is causing difficulty in falling asleep. The paracetamol acts as an analgesic to stop the pain, while the diphenhydramine induces drowsiness to help you rest.
Panadol Night is suitable for adults and children aged 16 years and over.
Do not use Panadol Night if you:
Speak to a healthcare professional before use if you:
Other ingredients: Maize starch, starch pre-gelatinised, potassium sorbate (E 202), povidone, purified talc, stearic acid, hypromellose (E 464), titanium dioxide (E 171), lactose monohydrate, macrogol 400, triacetin, brilliant blue FCF (E 133), indigo carmine (E 132) and carnauba wax.
Do not take for more than 7 nights in a row without consulting your doctor.
Common side effects:
Serious side effects (Stop use immediately):
GOOD Based on 184 reviews Posted on Google Bradley Robinson30/04/2026 Absolutely Amazing staff! Such a help thank you so muchPosted on Google Samiur Rahman30/04/2026 Best pharmacy in the UK. The staff here are very helpful, empathetic, understanding and compassionate. Brilliant customer service and staff are actual people who use their discretion to help people.Posted on Google Vivien donnellon29/04/2026 Extremely efficient and knowledgeable information given. All my questions were answered and also some advise regarding the issue. Thank you RehanaPosted on Google james watkins22/04/2026 Brilliant device ordered yesterday received it today
Page content authored by Amjad Khan, last reviewed by Dr Hussain Ahmad on 7th April 2026.




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