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Variety of delivery options including next day & free delivery.
Pharmacy, clinic and prescribers based in Greater Manchester.
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| Medication Name | Solpadeine Headache Soluble Tablets |
| Active Ingredients | Paracetamol 500mg and Caffeine 65mg |
| Medication Form | Effervescent (soluble) tablet |
| Used to Treat | Headache, migraine, backache, rheumatic pain, toothache, sore throat, period pain, fever, aches and pains of colds and flu |
| Available Pack Sizes | 16 tablets |
| Do you need a prescription? | Pharmacy-only medicine – don’t need a prescription but under supervision of pharmacist |
| How should it be taken? | Adults and children 16+: 2 tablets every 4-6 hours as required. Children 12-15: 1 tablet every 4-6 hours. |
| Patient Information Leaflet | Available in product packaging |
Solpadeine Headache Soluble Tablets are pain relief tablets that can provide effective relief from a range of everyday pain and fever symptoms, including:
Each tablet contains a dual-action formula of paracetamol 500mg and caffeine 65mg.
Paracetamol is a well-established painkiller that also reduces fever. It works by blocking the signals in the brain that tell your body it is in pain and by lowering elevated body temperature when you are unwell.
Caffeine is added to enhance paracetamol’s effectiveness. Research has shown that caffeine can increase the speed and extent of paracetamol absorption, helping provide fast, effective pain relief.
Adults and children over 16 years: Take 2 tablets dissolved in water every 4-6 hours as required. Do not take more than 8 tablets in 24 hours.
Children aged 12-15: Take 1 tablet every 4-6 hours as needed. Do not take more than 4 tablets in 24 hours.
Do not take more frequently than every 4 hours, and do not exceed the recommended dose.
Do not give to children under 12 years.
Avoid too much caffeine in drinks such as coffee and tea while taking this medicine, as high caffeine intake can cause difficulty sleeping, shaking and an uncomfortable feeling in the chest.
Like all medicines, Solpadeine Headache Soluble Tablets can cause side effects, though not everybody gets them. Generally, Solpadeine soluble tablets are well tolerated, and only a small number of people have had side effects.
Stop taking the tablets and tell your doctor immediately if you experience any of the following:
If you experience any side effects not listed here, speak to your doctor or pharmacist.
Active ingredients: Paracetamol 500 mg and Caffeine 65 mg per tablet.
Other ingredients: Sodium hydrogen carbonate, sorbitol (E420), saccharin sodium, sodium laurilsulfate, citric acid anhydrous, sodium carbonate anhydrous, povidone and dimeticone.
EXCELLENT Based on 121 reviews Posted on Hema Mehta06/09/2024 Very friendly and helpful. Moved my order to urgent as was needed in a certsin timeframe. So grateful for their help and service.Posted on Uju Udedibia30/08/2024 Great experience and an amazing, receptive and lovely staff. I recommend this pharmacy.Posted on Lindsey Whitaker22/08/2024 I had my blood taken today by the lovely lady at the pharmacy. It was a really great service and so reasonably priced. I will definitely be using their phlebotomy services again.Posted on Joanne Royle22/08/2024 Wonderful service I went for diabetes test after failing to getting sorted with my own doctors. Lady that did my test was fantastic. The staff are friendly and very welcoming. I would recommend them 100%. I will definitely use them again in the futurePosted on Ifeanyi Ohanyere16/08/2024 I visited the pharmacy to do a genotype test. The staff were so kind and supportive as I was coming from out of town. Turn around was quick. I highly recommend.
Solpadeine Headache Soluble Tablets are available over the counter without a prescription. You can buy Solpadeine headache soluble tablets online from Click2Pharmacy and have them delivered quickly and discreetly to your door.
You don’t need to take Solpadeine headache tablets with food. Simply dissolve the required number of tablets in a tumbler of water and drink the solution. If you find paracetamol-based medicines upset your stomach, taking them with or after food is a reasonable approach.
You can take soluble paracetamol every 4 to 6 hours as needed. Adults and children aged 16 and over should not take more than 8 tablets in 24 hours. Children aged 12 to 15 should not take more than 4 tablets in 24 hours. Never take a dose more frequently than every 4 hours.
Solpadeine Headache Soluble Tablets do not need to be refrigerated. Store them at room temperature below 30°C, and keep them out of reach and out of sight of children.
The effervescent format means the tablets dissolve quickly in water, which can help the active ingredients be absorbed faster than a standard tablet. Most people can expect to feel relief within 30 to 60 minutes of taking the recommended dose. If your headache persists or becomes more frequent, speak to your doctor.
Page content authored by Amjad Khan, last reviewed by Mr Muhammad on 9th March 2026.




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