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Royal Mail tracked 24 or 48 hour delivery in plain, unmarked packaging.
Pharmacy, clinic and prescribers based in Greater Manchester.
Where a prescription is needed, the price you see includes your consultation and prescription.
Fill in a quick online consultation for our licensed pharmacists to review.
Our pharmacists will review your treatment to ensure it’s suitable.
Your treatment will be delivered to your door quickly & discreetly.
Do you suffer from severe acne? Have you tried other treatments, but they have failed? Here are some key facts about Tetralysal oral antibiotic
| Medication Name | Tetralysal 300 |
| Active Ingredient | Lymecycline |
| Medication form | Oral hard capsules |
| Used to treat | Moderate to Severe acne Widespread acne Rosacea |
| Available as | Tetralysal 300mg Hard Capsules (28) |
| Other names by which this medication is known | Lymecycline 408mg Tetralysal acne capsules Tetralysal capsules, hard 408mg (28) |
| Common side effects | • Feeling sick • Stomach pain • Headache • Diarrhoea |
| Who is this medication suitable for | Children and adults over 12 |
| Do you need a prescription for it? | Yes |
| How should it be used? | One capsule a day |
| Patient Information Leaflet | Tetralysal Patient Information Leaflet |
Tetralysal 300 is a prescription-only oral antibiotic used to treat moderate to severe acne. Tetralysal belongs to a group of medicines called tetracyclines and can also be used to treat other infections. The generic (unbranded) version of Tetralysal is Lymecycline 408mg. You can also use this medicine when acne is present on larger areas, such as the back and chest.
Tetracycline acne medicine contains the active ingredient Lymecycline. The bacteria commonly associated with acne (Propionibacterium) feeds on excess sebum and causes the skin to become inflamed and produce whiteheads, blackheads, cysts, and pustules. Lymecycline attacks the bacteria, preventing growth, which reduces skin inflammation and acne spots.
Tetralysal 300mg is suitable for adults and children 12 years and older.
Click here Tetralysal information
Swallow one capsule daily with a full glass of water, preferably in the morning
Tetralysal 300 acne medicine should be taken for a minimum of 8 weeks. Antibiotics for acne typically take some time to work, so after 8 weeks, you can see if there is an improvement in your skin. You can take the capsules for up to 3 months.
Active Ingredient: Lymecycline 408mg
Other ingredients: magnesium stearate and colloidal hydrated silica, gelatine, titanium dioxide (E171), erythrosine (E127), quinoline yellow (E104) and indigotin (E132)
Medicines such as Tetralysal can have side effects. The most common are:
Other less common side effects can include:
If you experience any severe side effects, such as swelling in the face or throat, difficulty breathing, skin lesion, or severe headaches, you must stop taking this medicine immediately and seek medical help. Please read the patient information leaflet (PIL) for all the side effects before taking Tetralysal 300mg.
Keep out of the SIGHT and REACH of children
If you are pregnant or breastfeeding, you CANNOT use Tetralysal 300 for acne. It can be passed into the placenta and the mother’s milk. If you are trying to get pregnant, please speak to your doctor about taking this medicine.
Tetralysal must NOT be given to children under the age of 8, as it can lead to tooth discolouration.
If you are taking another type of acne medication called oral retinoids, you cannot take Tetralysal tablets at the same time.
For more information on Tetralysal and pregnancy or breastfeeding click here
If you need help deciding if Tetralysal is the right acne treatment for you, speak to one of our pharmacists, who will be happy to assist you. You should only buy Tetralysal online from a UK registered pharmacy. At Click2Pharmacy, we have an online clinic where we can issue prescription medicines. Simply fill out a consultation form, and once approved, you can order your medication direct from us.
Tetralysal/ Lymecycline can be used by children 12-18 years of age. However, Click2Pharmacy can only prescribe this medicine to those over 18. If you are younger than 18, speak to your own GP who, can decide if Tetralysal is suitable for you.
It is recommended to take Tetralysal for acne for at least 8 weeks. You should not take this medicine longer than 3 months.
No, it is not safe for pregnant women to use Tetralysal prescription medicine. This also applies to breastfeeding mothers.
Tetralysal can be used alongside acne treatments that you applied to your skin. These may contain either benzoyl peroxide or azelaic acid such as:
You cannot take other oral antibiotics or oral retinoids with this treatment.
Antibiotics such as Tetralysal can be prescribed for rosacea, as some symptoms such as redness and pimples are similar to acne. You will need to speak with your doctor about using Tetralysal for rosacea.
Like all medicines, Tetralysal 300mg hard capsules do have side effects. Most people will not have any problems, but common side effects can be nausea, stomach pain and diarrhoea. It is important to read the patient information leaflet (PIL) for a complete list of side effects.
Tetralysal acne treatment are oral antibiotics used to treat all types of bacterial infections. This includes Propionibacterium- the bacteria that causes acne. Tetralysal capsules are the same as Lymecycline 408mg capsules- the only difference is that Tetralysal is a brand name. Typically, antibiotics are taken when acne is severe or when other topical treatments alone have failed.
If you have acne on larger areas such as the shoulders, back and chest, then takin an antibiotic pill is more convenient than applying creams and gels. The key ingredient Lymecycline is responsible for directly attacking the acne-causing bacteria, leading to fewer spots and clearer skin.
You will need to give the capsules a chance to work; it can take around 8 weeks before you see any difference. We also recommend that you pair up Tetralysal/Lymecycline with a topical acne medicine that contains benzoyl peroxide (Epiduo gel and Acnecide gel) or azelaic acid (Skinoren and Finacea gel).
Dr Hussain Ahmad
Page content authored by Dr Hussain Ahmad, last reviewed by Amjad Khan on 18th December 2025.
