Tetralysal® 300 mg Capsules (28)


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Key Features

  • Once daily dose
  • Antibiotic dealing with the cause of Acne
  • Can be taken with Non antibiotic creams such as Differin, Epiduo, Fineaca
  • Buy online from a UK licensed pharmacy following a free consultation

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Tetralysal acne treatment - A view from our expert

Sakib Mohammed

Sakib Mohammed

Advance Pharmacist Prescriber

“Tetralysal acne treatment are oral antibiotics used to treat all types of bacterial infections. This includes Propionibacterium- the bacteria that causes acne. Tetralysal capsules are the same as Lymecycline 408mg capsules- the only difference is that Tetralysal is a brand name. Typically, antibiotics are taken when acne is severe or when other topical treatments alone have failed.

If you have acne on larger areas such as the shoulders, back and chest, then takin an antibiotic pill is more convenient than applying creams and gels. The key ingredient Lymecycline is responsible for directly attacking the acne-causing bacteria, leading to fewer spots and clearer skin.

You will need to give the capsules a chance to work; it can take around 8 weeks before you see any difference. We also recommend that you pair up Tetralysal/Lymecycline with a topical acne medicine that contains benzoyl peroxide (Epiduo gel and Acnecide gel) or azelaic acid (Skinoren and Finacea gel).

Tetralysal 300

Tetralysal 300 Key Facts:

Do you suffer from severe acne? Have you tried other treatments, but they have failed? Here are some key facts about Tetralysal oral antibiotic

Medication NameTetralysal 300
Active IngredientLymecycline
Medication formOral hard capsules
Used to treatModerate to Severe acne
Widespread acne
Available asTetralysal 300mg Hard Capsules (28)
Other names by which this medication is knownLymecycline 408mg
Tetralysal acne capsules
Tetralysal capsules, hard 408mg (28)
Common side effects
• Feeling sick
• Stomach pain
• Headache
• Diarrhoea
Who is this medication suitable forChildren and adults over 12
Do you need a prescription for it?Yes
How should it be used?One capsule a day
Patient Information LeafletTetralysal Patient Information Leaflet

How can I buy Tetralysal online? 

If you need help deciding if Tetralysal is the right acne treatment for you, speak to one of our pharmacists, who will be happy to assist you. You should only buy Tetralysal online from a UK registered pharmacy. At Click2Pharmacy, we have an online clinic where we can issue prescription medicines. Simply fill out a consultation form, and once approved, you can order your medication direct from us.

The Benefits of Tetralysal Hard Capsules:

  • Kills acne causing bacteria
  • Suitable for severe acne
  • One capsule a day
  • 3 month course recommended

What is Tetralysal 300?

Tetralysal 300 is a prescription-only oral antibiotic used to treat moderate to severe acne. Tetralysal belongs to a group of medicines called tetracyclines and can also be used to treat other infections. The generic (unbranded) version of Tetralysal is Lymecycline 408mg. You can also use this medicine when acne is present on larger areas, such as the back and chest.

How does Tetralysal acne medicine work?

Tetracycline acne medicine contains the active ingredient Lymecycline. The bacteria commonly associated with acne (Propionibacterium) feeds on excess sebum and causes the skin to become inflamed and produce whiteheads, blackheads, cysts, and pustules. Lymecycline attacks the bacteria, preventing growth, which reduces skin inflammation and acne spots.

Who is Tetralysal 300mg suitable for?

Tetralysal 300mg is suitable for adults and children 12 years and older.

Click here Tetralysal information

How to use Tetralysal 300mg Capsule

Swallow one capsule daily with a full glass of water, preferably in the morning

How quickly will I see results with Tetralysal 300 acne medicine?

Tetralysal 300 acne medicine should be taken for a minimum of 8 weeks. Antibiotics for acne typically take some time to work, so after 8 weeks, you can see if there is an improvement in your skin. You can take the capsules for up to 3 months.

Tetralysal 28 caps 300 mg Ingredients

Active Ingredient: Lymecycline 408mg

Other ingredients: magnesium stearate and colloidal hydrated silica, gelatine, titanium dioxide (E171), erythrosine (E127), quinoline yellow (E104) and indigotin (E132)

Tetralysal side effects

Medicines such as Tetralysal can have side effects. The most common are:

  • Nausea/ feeling sick
  • Abdominal pain
  • Headache
  • Diarrhoea

Other less common side effects can include:

  • Dizziness
  • Vomiting
  • Fever
  • Inflammation of the gut
  • Skin reactions
  • Sensitivity to sunlight

If you experience any severe side effects, such as swelling in the face or throat, difficulty breathing, skin lesion, or severe headaches, you must stop taking this medicine immediately and seek medical help. Please read the patient information leaflet (PIL) for all the side effects before taking Tetralysal 300mg.

Keep out of the SIGHT and REACH of children

Tetralysal Warnings

If you are pregnant or breastfeeding, you CANNOT use Tetralysal 300 for acne. It can be passed into the placenta and the mother’s milk. If you are trying to get pregnant, please speak to your doctor about taking this medicine.

Tetralysal must NOT be given to children under the age of 8, as it can lead to tooth discolouration.

If you are taking another type of acne medication called oral retinoids, you cannot take Tetralysal tablets at the same time.  

For more information on Tetralysal and pregnancy or breastfeeding click here

How can I buy Tetralysal hard capsules online?

Tetralysal hard capsules are a prescription-only medicine. You cannot buy Tetralysal over-the-counter from any pharmacy or online retailer. Please ensure you purchase this medicine from a UK registered pharmacy. At Click2Pharmacy, we have an online clinic where we issue prescription-based acne treatments.

Can I use Tetralysal/ Lymecycline if I’m under the age of 18?

Tetralysal/ Lymecycline can be used by children 12-18 years of age. However, Click2Pharmacy can only prescribe this medicine to those over 18. If you are younger than 18, speak to your own GP who, can decide if Tetralysal is suitable for you.

How long do I take Tetralysal for acne?

It is recommended to take Tetralysal for acne for at least 8 weeks. You should not take this medicine longer than 3 months.

Is it safe for pregnant women to use Tetralysal prescription medicine?

No, it is not safe for pregnant women to use Tetralysal prescription medicine. This also applies to breastfeeding mothers.

Can Tetralysal antibiotic be used with other acne treatments?

Tetralysal can be used alongside acne treatments that you applied to your skin. These may contain either benzoyl peroxide or azelaic acid such as:

You cannot take other oral antibiotics or oral retinoids with this treatment. 

Can I take Tetralysal for rosacea?

Antibiotics such as Tetralysal can be prescribed for rosacea, as some symptoms such as redness and pimples are similar to acne. You will need to speak with your doctor about using Tetralysal for rosacea.

Do Tetralysal 300mg hard capsules have side effects?

Like all medicines, Tetralysal 300mg hard capsules do have side effects. Most people will not have any problems, but common side effects can be nausea, stomach pain and diarrhoea. It is important to read the patient information leaflet (PIL) for a complete list of side effects.

Tetralysal 300 mg acne reviews

Have you used Tetralysal 300mg? Please let us know about your experience. Please leave a review below


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Customer Reviews

Based on 68 reviews
Ibrahim Ahsan
Ibrahim Ahsan
Very helpful staff, never had any issues with this pharmacy, 100% recommend
Julie Beardsley
Julie Beardsley
Very professional service. Just like having your very own pharmacist. Brilliant
Mohammed Khan
Mohammed Khan
Just had private bloods taken short wait time very thorough good price nice lady would recommend.
Sarah Smithies
Sarah Smithies
It is great to have somewhere local that does blood testing. The staff are lovely, helpful and experienced. They fit me in last minute. There is never a wait and the results back within a day or two.
After refusal of doctors appointment same old same old ring back etc. I was invited at 5.25 to see doctor I drove over immediately. Everything fully explained and checked over I was leaving by 6pm with penicillin for strep throat. Had I followed my doctors receptionist I would probably have suffered longer and increased the chances of a worse infection.I Great efficient service.
Lisa Lowther
Lisa Lowther
Fantastic service went for blood done very fast very friendly fantastic customer service

Tetralysal Reviews

Used for:

Tetralysal Capsules is indicated for the treatment of Acne caused by bacteria


Instructions for use:

The usual dosage for the chronic treatment of acne is 1 capsule daily (300 mg/day): treatment should be continued for at least 8 weeks.

Do not use with Antibiotic creams. Can be used with other Acne Creams

Take with plenty of water

Due to the risks of photosensitivity, it is recommended to avoid exposure to direct sunlight and ultraviolet light during the treatment which should be discontinued if any reaction occurs

Keep out of the SIGHT and REACH of children


Active Ingredients:  Lymecycline

Patient Information Leaflet: https://www.medicines.org.uk/emc/files/pil.926.pdf