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Zyban MR Tablets

  • Prescription tablets for quitting smoking
  • Reduces nicotine cravings and withdrawal
  • Supports quitting with behavioural support
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Fast & Free Delivery Options

Variety of delivery options including next day & free delivery.

100% UK-based Pharmacy

Pharmacy, clinic and prescribers based in Greater Manchester.

Free Online Consultations

Start your treatment with a quick and free online consultation.

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About Zyban MR Tablets

Zyban MR Tablets contain bupropion hydrochloride 150 mg in a modified-release tablet form. They are a prescription-only medicine designed to help adult smokers quit by reducing nicotine cravings and easing withdrawal symptoms during a quit attempt. Zyban MR works best when combined with motivational support or a structured smoking cessation programme.

Medication Name Zyban MR 150 mg Tablets
Active Ingredient Bupropion hydrochloride 150 mg
Other Ingredients Microcrystalline cellulose, hypromellose, cysteine hydrochloride monohydrate, magnesium stearate, macrogol 400, titanium dioxide, carnauba wax, and iron oxide black
Medication Form Modified/Prolonged-Release Tablet
Used to Treat Smoking cessation aid with motivational support
Available Strength 150 mg per tablet
Who Can Use It Adults aged 18 years and over
Prescription Required? Yes – Prescription only medicine
Patient Information Leaflet Zyban MR Tablets – Patient Information Leaflet

What Is Zyban MR Used For?

Zyban MR Tablets are used as an aid to help adults stop smoking. They reduce nicotine cravings and withdrawal symptoms such as irritability, anxiety, and restlessness, supporting successful quitting when used alongside behavioural support.

Who Is Zyban MR Suitable For?

Zyban MR is suitable for adults aged 18 and over who are motivated to quit smoking.

Do not use Zyban MR if you:

  • Are allergic to bupropion or any tablet ingredients
  • Have a history of seizures, epilepsy, or eating disorders
  • Are taking other medicines containing bupropion
  • Have severe liver problems
  • Are undergoing abrupt withdrawal from alcohol or sedatives

Consult a healthcare professional before use if you:

  • Have cardiovascular disease, high blood pressure, or mental health conditions
  • Are pregnant or breastfeeding
  • Take medicines that may interact with bupropion

How to Use Zyban MR Tablets

  1. Take Zyban MR exactly as prescribed by your doctor.
  2. Start with one 150 mg tablet once daily for the first 6 days.
  3. From day 7, take one 150 mg tablet twice daily, with at least 8 hours between doses.
  4. Swallow tablets whole — do not chew, crush, or break them.

Possible Side Effects of Zyban MR

Common side effects:

  • Insomnia or sleep disturbances
  • Dry mouth
  • Dizziness
  • Headache

Serious but less common side effects:

  • Seizures (dose-related risk)
  • Severe allergic reactions
  • Changes in mood or behaviour

Warnings and Precautions

  • Do not exceed the recommended dose.
  • Monitor blood pressure during use.
  • Use caution if you have a history of mental health disorders.
  • Avoid alcohol while taking Zyban MR.

Storage Instructions

  • Store below 25°C in original packaging.
  • Keep out of reach of children.
  • Do not use after the expiry date.

Zyban MR Tablets Reviews

Our Experienced UK-based Pharmacy Team

Clinical Consultant
MUDr, MRCEM, EBCEM, FRCEM
GMC no. 7176414

Pharmacist
MPharm
GPhC no. 2065469

Pharmacist
MPharm
GPhC no. 2046514

Page content authored by Amjad Khan, last reviewed by Mr Muhammad on 15th January 2026.

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