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Circadin (Melatonin) Tablets

  • Prolonged-release melatonin tablets to improve sleep quality
  • Designed specifically for adults aged 55 and over
  • Mimics natural hormone release to treat primary insomnia
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Fast & Free Delivery Options

Variety of delivery options including next day & free delivery.

100% UK-based Pharmacy

Pharmacy, clinic and prescribers based in Greater Manchester.

Free Online Consultations

Start your treatment with a quick and free online consultation.

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About Circadin Melatonin Tablets

Circadin 2mg Tablets are a prolonged-release medication containing the active ingredient melatonin. Melatonin is a naturally occurring hormone produced by the body that helps regulate the sleep-wake cycle. Circadin is specifically formulated to treat primary insomnia characterized by poor sleep quality in patients aged 55 years or older. By releasing melatonin gradually over several hours, it mimics the body’s natural rhythm to help you fall asleep faster and improve the overall quality of your rest.

Circadin is available in a convenient blister pack:

  • Circadin 2mg Prolonged-Release Tablets – 30 Tablets
Medication Name Circadin 2mg Prolonged-Release Tablets
Active Ingredient Melatonin 2mg
Medication Form Prolonged-release tablet
Used to Treat Primary insomnia (poor quality of sleep)
Available Sizes 30-tablet pack
Who Can Use It Adults aged 55 years and over
Prescription Required? Yes – Prescription Only Medicine (POM)
Patient Information Leaflet Circadin – Patient Information Leaflet

What Is Circadin Used For?

Circadin is used for the short-term treatment of primary insomnia in adults aged 55 and over. “Primary” means the insomnia does not have an established medical, mental, or environmental cause. It works by supplementing the body’s natural supply of melatonin, helping to restore a healthy sleep pattern and reducing the time it takes to fall asleep.

Who Is Circadin Suitable For?

Circadin is suitable for adults aged 55 years and older experiencing persistent sleep difficulties.

Do not take Circadin if you:

  • Are allergic to melatonin or any of the other ingredients in this medicine.

Speak to a healthcare professional before use if you:

  • Have liver or kidney problems.
  • Suffer from an autoimmune disease (where the body is attacked by its own immune system).
  • Have been told you have an intolerance to certain sugars (contains lactose).
  • Are pregnant or breast-feeding, as use is not recommended in these cases.

Ingredients

Other ingredients: Ammonio methacrylate copolymer type B, calcium hydrogen phosphate dihydrate, lactose monohydrate, silica (colloidal anhydrous), talc and magnesium stearate.

How to Take Circadin Tablets

  1. Take one tablet once a day.
  2. Administer the dose 1 to 2 hours before you plan to go to sleep.
  3. Take the tablet after eating a meal.
  4. Swallow the tablet whole with water. Do not break, crush, or chew it, as this destroys the prolonged-release properties.
  5. Avoid drinking alcohol before or after taking Circadin, as it reduces the effectiveness of the medication.

Possible Side Effects of Circadin

Common side effects are rare, but some people may experience:

  • Irritability, nervousness, or restlessness
  • Migraine or headaches
  • Dizziness or somnolence (tiredness)
  • Abdominal pain or dry mouth

Uncommon or rare side effects:

  • Night sweats
  • Weight gain
  • Visual impairment or watery eyes
  • Increased blood pressure

Warnings and Precautions

  • Drowsiness: Circadin may cause drowsiness; do not drive or operate machinery if affected.
  • Alcohol: Avoid alcohol consumption as it interferes with the sleep-promoting effects of the active ingredient.
  • Smoking: Smoking may increase the breakdown of melatonin by the liver, potentially making the tablets less effective.
  • Other Medicines: Inform your doctor if you take fluvoxamine, psoralens, cimetidine, or benzodiazepines.

Storage Instructions

  • Store below 25°C.
  • Store in the original package in order to protect from light.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date stated on the carton.

 

Circadin (Melatonin) Tablets Reviews

Our Experienced UK-based Pharmacy Team

Clinical Consultant
MUDr, MRCEM, EBCEM, FRCEM
GMC no. 7176414

Pharmacist
MPharm
GPhC no. 2065469

Pharmacist
MPharm
GPhC no. 2046514

Page content authored by Amjad Khan, last reviewed by Dr Hussain Ahmad on 13th April 2026.

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