Emergency contraceptive pills in blister pack for 'how effective is the morning after pill'

How effective is the morning after pill?

If you’ve had unprotected sex or your contraception has failed, you’ll want to know how well the emergency contraceptive pill actually works.

Effectiveness depends on which type you take, how quickly you act, and a few personal factors.

Types of Emergency Contraception: Effectiveness Compared

There are three types of emergency contraception available in the UK.

TypeEffectivenessTime WindowPregnancies Prevented
ellaOne (ulipristal acetate)Up to 99%Within 120 hours (5 days)95%+ of expected pregnancies
Levonorgestrel (e.g. Levonelle)Up to 95%Within 72 hours (3 days)85% of expected pregnancies
Copper IUD (emergency IUD)99.9%+Within 120 hours (5 days)99%+ of expected pregnancies

When contraception is listed as “up to 99% effective”, it describes relative risk reduction, meaning how much emergency contraception lowers your pregnancy risk compared to not taking anything.

For example, if 100 women have unprotected sex at a fertile time, roughly 8 would get pregnant without any contraception. When you use emergency contraception, that drops to 1 to 3 with levonorgestrel, around 1 with ellaOne, and fewer than 1 in 1,000 with the copper IUD.

How long is the morning after pill effective?

Both pills should be taken as soon as possible. It’s more effective the sooner you take it after unprotected sex, so don’t wait to see if your period arrives on time.

Levonelle (Levonorgestrel)

Levonelle must be used within 3 days after unprotected sex, but effectiveness declines quickly:

After 72 hours, Levonellel is not recommended.

ellaOne (Ulipristal Acetate)

ellaOne is the most effective hormonal option, and can be used within 5 days (120 hours) of unprotected sex. It’s more effective if you take it earlier, but unlike levonorgestrel, it maintains consistent effectiveness throughout the full window with no sharp decline. 

Pregnancy rates are 0.9-1.8% when used within 120 hours, with no significant difference between 72 and 120 hours.

ellaOne prevents roughly twice as many pregnancies as levonorgestrel overall, and up to 2.5 times as many in the first 24 hours.

When should you take the morning after pill?

Both pills work by delaying ovulation. Once ovulation has already happened, neither can reliably prevent pregnancy.

Where possible, take ellaOne as it is the better option in most situations. It is particularly important if:

  • You’re between 72 and 120 hours post-unprotected sex
  • You think you may be close to ovulation
  • You’ve already used levonorgestrel earlier in the same cycle
A Graph Showing When You Should Take The Morning After Pill

If levonorgestrel is your only option, take it. It’s still significantly better than not taking anything.

Factors That Affect Morning After Pill Effectiveness

Weight and BMI

Weight has a significant effect on levonorgestrel specifically. Pregnancy risk increases sharply from around 70 to 75 kg, and at approximately 80kg, pregnancy risk reaches 6% or higher, comparable to taking no contraception at all.

ellaOne is less affected by BMI, though some reduction in effectiveness does happen at higher weights. At higher body weights, drug levels may fall below those needed to delay ovulation, particularly with levonorgestrel.

BMI RangeLevonorgestrelellaOneRecommendation
Under 25Standard effectivenessStandard effectivenessEither pill suitable
25 to 30Reduced; risk rises from around 70 to 75 kgSlightly reduced; still better than levonorgestrelellaOne preferred
Over 30Significantly reduced –  the risk of pregnancy is similar to what might be expected without any contraceptionSome reduction – still more effective than levonorgestrelCopper IUD first-line; ellaOne second-line

Where You Are in Your Cycle

Emergency pills work by delaying the release of an egg and cannot reverse ovulation once it has happened. Conception probability peaks around day 13, with fertile window chances rising from around 2% early in the cycle to 58% mid-cycle before falling again.

How effective is the morning after pill during ovulation?

  • Days 10 to 17 (ovulation window): Highest risk. Pills help if taken before ovulation, but are much less effective once you’ve started ovulating. The copper IUD or ellaOne are the best options.
  • Follicular phase (early cycle): Moderate risk. Pills are generally effective at this stage.
  • Luteal phase (after ovulation): Lower risk; pills are unlikely to be needed.
  • During menstruation: Minimal risk.

Medications That Interact With Levonorgestrel

Certain medicines speed up the liver metabolism of levonorgestrel, reducing its effectiveness.

Levonorgestrel is metabolised by the CYP3A4 enzyme, and drugs that induce this enzyme lower circulating levonorgestrel levels in your bloodstream. This includes some forms of hormonal contraception, like the combined pill, which may interact with ulipristal acetate and reduce its effectiveness.

These include:

  • Antiepileptics: carbamazepine, phenytoin, phenobarbital, primidone, topiramate
  • TB antibiotics: rifampicin, rifabutin
  • St John’s Wort

If you’ve taken any of these in the past four weeks:

What if the morning after pill doesn’t work?

Emergency contraception is highly effective, but not 100%. If you do become pregnant after taking the morning after pill, failure rates are low: around 1-3 in 100 for levonorgestrel and 1-2 in 100 for ulipristal acetate.

Failure is more likely if:

  • Ovulation had already happened when you took the pill
  • You took it close to the end of the recommended window
  • You had multiple episodes of unprotected sex in the same cycle
  • You have a higher BMI and used levonorgestrel

Take a pregnancy test if your period is 7 or more days late, or if you experience pregnancy symptoms like breast tenderness, nausea, or fatigue three weeks after taking emergency contraception. A period that is significantly lighter or heavier than usual is also worth investigating.

Morning After Pill Side Effects vs Pregnancy Symptoms

Side effects from emergency contraception, including nausea, headache, and irregular bleeding, are common, usually mild, and short-lived. If you vomit within 2 hours of taking the pill, it may not have been absorbed properly, and you should seek advice about taking another dose. 

Only a small number of women experience symptoms that closely mimic early pregnancy. If symptoms persist beyond a few days of taking, take a pregnancy test.

Can you take the morning after pill more than once?

The morning after pill shouldn’t be used as a regular method of contraception. Each use covers that episode of unprotected sex, but it is not designed to replace ongoing methods.

Repeated use increases the cumulative risk of taking it too late in the cycle. One study found failures occurred in about 1% of levonorgestrel users in the first month, with none of the copper IUD users becoming pregnant.

If you’re relying on regular contraception that has failed, or find yourself needing emergency contraception repeatedly, it’s worth speaking with a doctor or pharmacist about a more reliable ongoing method.

Get Emergency Contraception from Click2Pharmacy

If you need emergency contraception, our online clinic makes it easy to access the right option quickly and discreetly, from the comfort of your own home.

Simply complete our short health questionnaire and one of our pharmacists will review your answers to confirm which option is suitable for you. If approved, your medication will be dispatched promptly in discreet packaging.

Need emergency contraception now? Start your consultation today. The sooner you act, the more effective it will be.

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