Zindaclin 1% Gel (30g)

Zindaclin 1% Gel for Acne Treatment

What is Zindaclin Gel Used For?

Zindaclin Gel is a prescription treatment for acne vulgaris. It’s designed to treat mild to moderate acne by targeting the bacteria that contribute to spots and inflammation.

Zindaclin 1% Gel is particularly useful when over-the-counter acne treatments haven’t been effective enough. It helps reduce the number of breakouts, calms redness in inflamed areas, and prevents pores from becoming blocked.

Unlike creams or washes that you rinse off, Zindaclin Gel stays on your skin throughout the day, working continuously to keep acne-causing bacteria under control. You’ll need to use it consistently for several weeks before seeing noticeable improvements, with the best results typically appearing after a few months of regular use.

How Does Zindaclin Gel Work?

Zindaclin contains clindamycin phosphate. Clindamycin is an antibiotic that works directly on your skin to combat acne.

The gel targets Cutibacterium acnes (previously known as Propionibacterium acnes), the bacteria that cause acne. These bacteria thrive in blocked pores and trigger inflammation, leading to red, swollen spots.

Clindamycin works by entering bacterial cells and stopping them from producing the proteins they need to survive and multiply. With fewer bacteria on your skin, there’s less inflammation, and your pores are less likely to become blocked.

Because Zindaclin Gel works gradually, you’ll need to be patient. Most people start noticing improvements after about 6 to 8 weeks of daily use, though it can take up to 12 weeks to see the full benefits.

Who Can Use Zindaclin Gel?

Zindaclin Gel is suitable for adults and adolescents aged 12 years and over who have mild to moderate acne.

However, Zindaclin may not be suitable for everyone. You should consult your doctor or pharmacist before using Zindaclin Gel if you:

• Are allergic to clindamycin, lincomycin, or any other ingredients in the gel
• Have a history of inflammatory bowel disease, such as Crohn’s disease or ulcerative colitis
• Have previously developed diarrhoea when taking antibiotics
• Are pregnant, planning to become pregnant, or breastfeeding
• Have very sensitive skin or other active skin conditions

If you develop severe or persistent diarrhoea while using Zindaclin Gel, stop treatment immediately and contact your doctor. Although rare with topical antibiotics, this could be a sign of a serious bowel condition.

Before starting treatment with Zindaclin, always inform your doctor or pharmacist about any medications you’re taking and any medical conditions you have.

How to Use Zindaclin Gel

Using Zindaclin Gel correctly is important for getting the best results and avoiding irritation:

1. Cleanse your skin with a mild, non-comedogenic cleanser, then pat dry. Allow your skin to dry completely before applying the gel.
2. Apply a thin layer of Zindaclin Gel to the area where you usually get spots. Don’t just apply it to individual pimples – spread it across all the areas of skin where you typically get breakouts, to prevent them from forming.
3. Gently rub the gel in until it’s absorbed. Avoid getting the product in your eyes, mouth, lips, or inside your nose. If accidental contact occurs, rinse thoroughly with water.
4. Wash your hands after application and make sure the cap is tightly closed.
5. You can apply moisturiser or other skincare products after Zindaclin has been absorbed, but wait a few minutes to let the gel settle into your skin first.

Don’t apply thick layers or use Zindaclin more often than prescribed, as this won’t speed up results and may increase irritation. Continue using the gel as directed, even if your skin improves, to help prevent acne from returning.

If you miss a dose, simply apply it as soon as you remember, unless it’s nearly time for your next application. Don’t apply a double amount to make up for a missed dose.

Zindaclin Gel Side Effects

Like all medications, Zindaclin Gel can cause side effects, although not everyone experiences them. Most side effects are mild and affect the area of the skin where the treatment was applied.

Common Side Effects​

• Dry, red, or irritated skin
• Mild burning or stinging sensation after application
• Itchy skin
• Skin peeling or flaking
• Temporary worsening of acne (this can happen in the first few weeks as your skin adjusts)

Uncommon Side Effects

• Oily or greasy skin
• Contact dermatitis (skin inflammation)
• Eye irritation if used too close to the eye area

Serious Side Effects

While serious side effects are rare with topical clindamycin, contact your doctor immediately if you experience:

• Severe or persistent diarrhoea, especially if there is blood or mucus (this could indicate a serious bowel condition)
• Signs of an allergic reaction, such as swelling of the face or throat, severe rash, or difficulty breathing
• Severe skin irritation or blistering

If you experience any side effects, particularly if they’re severe or persistent, contact your doctor or pharmacist. Most mild side effects will settle down as your skin adjusts to the treatment. Using a light, oil-free moisturiser can help if your skin feels dry or tight.

You can report side effects to the MHRA (Medicines and Healthcare products Regulatory Agency) via the Yellow Card Scheme to help monitor the safety of the medication.

Zindaclin Gel Ingredients

Active ingredient: Clindamycin phosphate 1% (equivalent to 1% clindamycin)

Other ingredients: Propylene glycol, purified water, ethanol, zinc acetate, hydroxyethylcellulose, sodium hydroxide

The gel contains ethanol (alcohol), which may cause a brief burning sensation on damaged or very sensitive skin. It also contains propylene glycol, which can cause skin irritation in some people.

Zindaclin Gel Alternative​s

If Zindaclin Gel isn’t suitable for you or you’d like to explore other acne treatment options, there are several alternatives available:

Differin Gel/Cream (Adapalene)

A retinoid that helps prevent clogged pores and normalises skin cell turnover. Differin is a good non-antibiotic option and is often recommended for longer-term acne maintenance.

Duac Gel (Clindamycin + Benzoyl Peroxide)

Combines the same antibiotic as Zindaclin (clindamycin) with benzoyl peroxide for dual action against bacteria and blocked pores. This can be more effective than using an antibiotic alone.

Epiduo Gel (Adapalene + Benzoyl Peroxide)

Combines a retinoid with benzoyl peroxide to target both blocked pores and acne-causing bacteria. This is particularly useful for moderate acne.

Finacea Gel (Azelaic Acid)

A gentler alternative that reduces inflammation and helps fade red marks left by acne. It’s often chosen for sensitive skin or when antibiotics aren’t suitable.

Skinoren Cream (Azelaic Acid)

Similar to Finacea but in a cream formulation, which some people with dry skin prefer.

Zindaclin Gel Warnings

• For external use only. Avoid contact with the eyes, mouth, lips, and inside of the nose. If accidental contact occurs, rinse thoroughly with water.
• Don’t use Zindaclin on broken, damaged, or irritated skin, including areas with cuts, scrapes, or eczema.
• Avoid using other topical acne treatments containing abrasive agents, strong astringents, or products that dry the skin (like benzoyl peroxide or salicylic acid) unless your doctor advises otherwise, as this may increase irritation.
• Keep out of sight and reach of children.
• Store below 25°C and do not freeze.
• Do not use after the expiry date printed on the packaging.