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Prochlorperazine Buccal Tablets

  • Fast relief for migraine-related nausea
  • Dissolves on the gum—no swallowing required
  • Bypasses the stomach for quicker absorption
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£6.49
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Fast & Free Delivery Options

Variety of delivery options including next day & free delivery.

100% UK-based Pharmacy

Pharmacy, clinic and prescribers based in Greater Manchester.

Free Online Consultations

Start your treatment with a quick and free online consultation.

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About Prochlorperazine Buccal Tablets

Prochlorperazine Buccal Tablets contain prochlorperazine maleate 3mg, a medication specifically formulated to provide fast-acting relief from nausea and vomiting associated with migraines. Unlike standard oral tablets, these are “buccal” tablets, meaning they dissolve against the gum to enter the bloodstream directly, making them ideal for patients who find it difficult to swallow or keep down medication due to feeling sick.

Prochlorperazine 3mg tablets (generic Buccastem M) are effective for the treatment of:

  • Nausea (feeling sick)
  • Vomiting (being sick)
  • Sickness associated with migraine headaches
Medication Name Prochlorperazine 3mg Buccal Tablets
Active Ingredient Prochlorperazine Maleate 3mg
Medication Form Muco-adhesive buccal tablet
Used to Treat Nausea and vomiting associated with migraine
Available Sizes 8-tablet pack
Who Can Use It Adults aged 18 years and over
Prescription Required? No – Pharmacy (P) medicine

What Is Prochlorperazine Buccal Used For?

Prochlorperazine Buccal tablets are primarily used to stop feeling sick (nausea) and being sick (vomiting) caused by migraines. Because the tablet dissolves in the mouth, the active ingredient bypasses the digestive system, providing relief even if you are actively vomiting.

Who Is Prochlorperazine Buccal Suitable For?

This medication is suitable for adults aged 18 and over who have been previously diagnosed with migraine by a doctor.

Do not use Prochlorperazine Buccal Tablets if you:

  • Are allergic to prochlorperazine or any listed ingredients
  • Are pregnant or breastfeeding
  • Have liver problems or blood disorders
  • Have epilepsy or Parkinson’s disease
  • Have glaucoma or prostate problems

Speak to a healthcare professional before use if you:

  • Are elderly (increased risk of side effects)
  • Have heart disease or a history of blood clots
  • Have a history of stroke
  • Are taking other medications, particularly sedatives or blood pressure medicine

Ingredients

Other ingredients: sucrose, locust bean gum, xanthan gum, hypromellose 2910, riboflavin sodium phosphate, magnesium stearate and talc.

How to Use Prochlorperazine Buccal Tablets

  1. Use your tongue to find a comfortable spot high up on the gum, under your upper lip.
  2. Place the tablet between the top of your gum and your lip.
  3. Leave the tablet to dissolve completely; this usually takes between 1 and 2 hours.
  4. Do not chew, suck, or swallow the tablet.
  5. Most people find it easiest to use after a meal.

If you wear dentures, the tablet can be placed in any comfortable position between the lip and the gum.

Possible Side Effects of Prochlorperazine Buccal

Common side effects:

  • Drowsiness or dizziness
  • Dry mouth
  • Insomnia (difficulty sleeping)
  • Mild skin rashes

Rare:

  • Increased sensitivity to sunlight
  • Jaundice (yellowing of the skin/eyes)
  • Unusual muscle movements or tremors

If you experience swelling of the face, tongue, or throat, stop use immediately and seek medical attention.

Warnings and Precautions

  • Do not use for more than 2 days.
  • This medication may cause drowsiness; do not drive or operate machinery if affected.
  • Avoid alcohol while taking this medicine as it increases the sedative effect.
  • Contains sucrose; consult your doctor if you have an intolerance to some sugars.

Storage Instructions

  • Store below 25°C in the original package to protect from light.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date stated on the carton.

 

 

Prochlorperazine Buccal Tablets Reviews

Our Experienced UK-based Pharmacy Team

Clinical Consultant
MUDr, MRCEM, EBCEM, FRCEM
GMC no. 7176414

Pharmacist
MPharm
GPhC no. 2065469

Pharmacist
MPharm
GPhC no. 2046514

Page content authored by Amjad Khan, last reviewed by Dr Hussain Ahmad on 11th April 2026.

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