Xonvea Tablets

About Xonvea Tablets

Xonvea Tablets are a prescription-only medication containing 10mg doxylamine succinate and 10mg pyridoxine hydrochloride (Vitamin B6). This combination is specifically licensed for the treatment of nausea and vomiting during pregnancy (NVP), commonly known as morning sickness, in women who have not found relief through conservative management like diet or lifestyle changes.

Xonvea is a gastro-resistant, delayed-release tablet. This specialized formulation ensures the active ingredients are released at the optimal time to combat symptoms, typically taken at bedtime to provide relief throughout the following morning.

Xonvea Tablets are suitable for pregnant women aged 18 years and over.

What Are Xonvea Tablets Used For?

Xonvea is used to manage symptoms of nausea and vomiting of pregnancy (NVP) when non-medicinal treatments, such as eating small frequent meals or avoiding triggers, have failed. It combines an antihistamine (doxylamine) with Vitamin B6 (pyridoxine) to effectively reduce the feeling of sickness and the urge to vomit.

Who Are Xonvea Tablets Suitable For?

Xonvea is suitable for pregnant women 18+ who are suffering from morning sickness that has not responded to lifestyle adjustments.

Do not use Xonvea Tablets if you:

• Are allergic to doxylamine, pyridoxine, or any other ingredients in the tablet.
• Are allergic to other antihistamines derived from ethanolamine (such as diphenhydramine).
• Are taking medicines called Monoamine Oxidase Inhibitors (MAOIs) or have taken them in the last 14 days.
• Suffer from porphyria (a rare metabolic disorder).

Speak to a healthcare professional before use if you:

• Have asthma or increased pressure in the eye (glaucoma).
• Have a stomach ulcer or an obstruction in the bladder or gut.
• Have liver or kidney disease.
• Suffer from “Long QT syndrome” or other heart conditions.
• Are taking any other Vitamin B supplements.

How to Take Xonvea Tablets

1. Swallow the tablets whole with a drink of water.
2. Do not crush, chew, or split the tablets, as this destroys the delayed-release coating.
3. Take Xonvea on an empty stomach for the best absorption.
4. Follow the dosage schedule prescribed by your doctor, starting with two tablets at bedtime.
5. If you miss a dose, skip it and take the next dose at the usual time; do not take a double dose.

Xonvea should be taken daily and not just “as needed” to ensure consistent symptom control.

Possible Side Effects of Xonvea Tablets

Very common (may affect more than 1 in 10 people):

• Feeling very sleepy or drowsy (somnolence).

Common side effects:

• Dizziness or tiredness.
• Dry mouth.

Other potential effects:

• Blurred vision or dilated pupils.
• Constipation or urinary retention.
• Increased heart rate (palpitations).

If you experience any severe allergic reactions or unusual skin rashes, stop taking the medicine and seek medical help immediately.

Warnings and Precautions

• Drowsiness: Xonvea can cause significant sleepiness. Do not drive, cycle, or operate machinery while taking this medicine.
• Alcohol: Do not drink alcohol while using Xonvea, as it increases the risk of severe drowsiness and accidents.
• Breastfeeding: Xonvea is not recommended if you are breastfeeding, as it can pass into breast milk and may harm the baby.
• False Positives: This medicine may cause false positive results in some urine drug screens (e.g., for methadone or opiates).

Storage Instructions

• This medicine does not require any special storage conditions.
• Keep out of the sight and reach of children.
• Do not use after the expiry date stated on the carton and blister pack.